Adenosine Receptors presents the first single volume compilation of reviews on how adenosine, acting on its cellular receptors, regulates immune responses.

Features:

• Brings together the latest research from international experts representing both academia and industry
• Covers all aspects of biomedical research including cell biology, pharmacology, pathophysiology, and experimental medicine
• Investigates the adenosine connection with a myriad of challenging diseases including atherosclerosis and cancer, as well as autoimmune and nervous systems disorders
• Includes data derived from studies using cutting edge research techniques such as transgenic and knockout technologies

Contents

1. Adenosine Receptor Pharmacology
2. Medicinal Chemistry of Adenosine A3 Receptors
3. The role of CD73 in the Generation of Extracellular Adenosine for Adenosine Receptor Signaling
4. Regulation of Monocyte/Macrophage Function by Adenosine Receptors
5. Impaired Lymphocyte Activation in the Presence of Adenosine: Mechanisms and Physiologic Relevance
6. Adenosine and Neutrophil Functions
7. Dendritic Cells Regulated by Nucleotides and Nucleosides
8. Adenosine and Endothelial Cell Function
9. Adenosine A2B Receptor in the Intestinal Epithelia
10. Adenosine, Adenosine Receptors and the Regulation of Glial Cells in Neuronal Damage
11. Adenosine Receptors, Wound Healing and Angiogenesis
12. A2A Adenosine Receptors and Ischemia Reperfusion Injury
13. Adenosine Signaling in Chronic Lung Disease
14. Role of Adenosine in the Control of Inflammatory Events Associated with Acute and Chronic Neurodegenerative Disorders
15. Anti-Inflammatory And Cytoprotective Effects Of Inosine
16. Adenosine And Infection
17. Regulation of Peripheral Inflammation by Spinal Adenosine
18. Adenosine, Tumors and Immunity
19. Adenosine in Atherosclerosis
20. Regulation of Macrophage-Dependent Angiogenesis by Adenosine and Toll-Like Receptors

Index

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