Third edition
by Edward K. Wagner
Ideal for those seeking a solid understanding of the basic principles in this rapidly developing field, Basic Virology offers a comprehensive introduction to the fundamentals of virology. Featuring an enhanced art program now in full-color, the new edition has been updated throughout.
Features:
- Third edition incorporates additional reading suggestions, expanded review questions, chapter outlines and full-color artwork
- Contains new chapters dealing with viruses and cancer, generation and use of recombinant viruses and virus-like particles, viral evolution, network biology and viruses, and animal models and transgenics, as well as a chapter devoted to HIV and AIDS
- Downloadable artwork, original animations and online resources are available at recommended website
Contents
Part I: Virology and Viral Disease
- Introduction - the Impact of Viruses on Our View of Life
- An Outline of Virus Replication and Viral Pathogenesis
- Virus Disease in Populations and Individual Animals
- Patterns of Some Viral Diseases of Humans
Part II: Basic Properties of Viruses and Virus-Cell Interaction
- Virus Structure and Classification
- The Beginning and End of the Virus Replication Cycle
- Host Immune Response to Viral Infection - The Nature of the Vertebrate Immune Response
- Strategies to Protect Against and Combat Viral Infection
Part III: Working with Virus
- Visualization and Enumeration of Virus Particles
- Replicating and Measuring Biological Activity of Viruses
- Physical and Chemical Manipulation of the Structural Components of Viruses
- Characterization of Viral Products Expressed in the Infected Cell
- Viruses Use Cellular Processes to Express Their Genetic Information
Part IV: Replication Patterns of Specific Viruses
- Replication of Positive-sense RNA Viruses
- Replication Strategies of RNA Viruses Requiring RNA-directed mRNA
- Replication Strategies of Small and Medium-sized DNA Viruses
- Replication of Some Nuclear-replicating Eukaryotic DNA Viruses with Large
- Replication of Cytoplasmic DNA Viruses and "Large" Bacteriophages
- Retroviruses: Converting RNA to DNA
- Human Immunodeficiency Virus Type 1 (HIV-1) and Related Lentiviruses
- Hepadnaviruses: Variations on the Retrovirus Theme
Part V: Viruses: New Approaches and New Problems
- The Molecular Genetics of Viruses
- Molecular Pathogenesis
- Viral Bioinformatics and Beyond
- Viruses and the Future - Promises and Problems
Index