by Atta-ur Rahman,
M.I. Choudhary
and W. Thompson

Bioassay Techniques for Drug Development presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy.

The contents detail a number of enzyme-based assays, cell-based functional bioassays and receptor radioligand binding assays along with detailed descriptions of each type. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry or pharmacology.

Contents

1. Bench-Top Primary Bioassay Screening
   1. Toxicity Assays
   2. Antimicrobial Assays
   3. Antiviral and Anticancer Assays
   4. Antimitotic Assay
   5. Genotoxicity Assays
   6. Assays for Control of Tropical Diseases
   7. Assays for Agrochemicals
   8. Hepatoxicity Assays
   9. Hypoglycemic/Antidiabetic Activity Assays
   10. Diuretic Activity Assays
   11. Anthelminthic Assays
   12. Anti-fertility/Anti-implantation Assay
   13. In-vitro Assay for Platelet Aggregation
   14. Anti-inflammatory Assay
   15. Immunomodulating Assay
   16. Antiepileptic (Anticonvulsant) Assay
   17. Analgesic Assays
   18. Gastroprotective/Antiulcer Assays
   19. Radio-labeling Bioassays
   20. Anti-emitic Assay

2. High-Throughput Screening
   21. Enzyme Assays
   22. Cell-based Receptor Functional Assays
   23. Radioligand Binding Assays

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