edited by Nick Van Bruggen
and Timothy P.L. Roberts

• Presents a detailed review of the application of biomedical imaging techniques available for noninvasive laboratory animal research
• Emphasizes the versatility of MRI in experimental neuroscience research - from anatomy to function
• Provides concise, theoretical descriptions of physics with the biologist in mind
• Serves as a practical guide with focus on application and implementation

Emphasizing the relationship between physiological microenvironment and macroscopic imaging signal changes, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the noninvasive biomedical imaging techniques available for laboratory animal research. Focusing on MRI, but recognizing the multiple forms of imaging information, this book outlines the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. The book is intended for the biologist who may not have a background in the physical sciences. This applied guide also provides a concise theoretical description of the pertinent physics.

Noninvasive imaging offers the obvious benefits of reducing sample sizes and identifying new and unanticipated behaviors. Biomedical Imaging in Experimental Neuroscience presents detailed information for biologists interested in how biomedical imaging may augment their in vivo research and for clinical practitioners seeking deeper insights into the association between imaging findings and disease pathophysiology.

Contents

1. Principles of MRI Contrast
2. MRI Measurement of Cerebral Perfusion and Application to Experimental Neuroscience
3. MRI Measurement of Cerebral Water Diffusion and Its Application to Experimental Research
4. Functional Magnetic Resonance Imaging
5. Functional Imaging in Nonhuman Primates
6. Pharmacologic Magnetic Resonance Imaging (phMRI)
7. Anatomical Studies in the Rodent Brain and Spinal Cord: Applications of Magnetic Resonance Microscopy
8. Magnetic Resonance Spectroscopy: Principles and Applications
9. Small Animal Imaging with Positron Emission Tomography
10. MRI and Novel Contrast Agents for Molecular Imaging
11. The Future for Biomedical Imaging: Emerging and Alternative Technologies

click here to see books • videos • cd-roms of related interest