Biomimetic Materials and Design edited by Angela K. Dillow and M. Lowman

Biomedical Science Reference Book from C.H.I.P.S.

Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery

edited by Angela K. Dillow and M. Lowman

Covering significant advances in the field and providing more than 2000 contemporary references, Biomimetic Materials and Design is an essential source for biomedical engineers; physical, surface, colloid, and polymer chemists; chemical engineers; biochemists; biophysicists; biotechnologists; biomaterials specialists; materials scientists; and graduate-level students in these disciplines.

This reference volume describes the mechanisms and architecture of biological systems to formulate and design natural and synthetic compounds, degradable and non-degradable scaffolds, and targeted drug delivery devices-offering current strategies to control adhesive interactions, elicit specific cellular responses, and improve the biocompatability, performance, and durability of prosthetic materials.

Biomimetic Materials and Design presents methods to:

support and stimulate cellular processes such as migration and matrix deposition
develop synthetic and biological materials with enhanced in vivo properties
reproduce complex biological and physiological processes
modify the surface characteristics of synthetic materials, as well as events at the material-tissue interface

And discusses:

signal selection, density, and accessibility
surface grafting, micropatterning, and microimprinting
the identification and refinement of protein sequences
the formation of "smart" biomaterials for control of drug distribution

Contents:

Biointerfacial Strategies
1. Use of Supported Thin Films of Peptide Amphiphiles as Model Systems of the Extracellular Matrix to Study the Effects of Structure–Function Phenomena on Cell Adhesion
2. Engineering of Integrin-Specific Biomimetic Surfaces to Control Cell Adhesion and Function
3. Mimetic Peptide-Modified Materials for Control of Cell Differentiation
4. Effects of Substratum Topography on Cell Behavior
5. Cytomimetic Biomaterials: Fabrication, Characterization, and Applications
6. Micro- and Nanoscale Organizations of Proteins Modulate Cell-Extracellular Matrix Interactions: Lessons for the Design of Biomaterials
7. Cell Adhesion-Dependent Signaling Pathways on Biomaterials Surfaces
Tissue Engineering
1. Biomaterials: Synthetic and Engineering Strategies
2. Scaffolds for Directing Cellular Responses and Tissue Formation
3. Chitosan as a Molecular Scaffold for Biomimetic Design of Glycopolymer Biomaterials
4. "Cell-Internalizable" Ligand Microinterfaces on Biomaterials: Design of Regulatory Determinants of Cell Migration
5. Biomimetic Strategies and Applications in the Nervous System
6. Tissue Engineering Strategies for Axonal Regeneration Following Spinal Cord Injury
Targeted Drug Delivery
1. Micropatterning Biomimetic Materials for Bioadhesion and Drug Delivery
2. Bioinspired Engineering of Intelligent Drug Delivery Systems and Protein–Polymer Conjugates
3. Implantable Drug Delivery Devices: Design of a Biomimetic Interfacial Drug Delivery System
4. Pharmacologically Active Biomaterials
5. Biomimetic Lung Surfactant Replacements
6. Peptide Nucleic Acid (PNA) Conjugates in Biotechnology

Index

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Biomimetic Materials and Design:
Biointerfacial Strategies, Tissue Engineering,
and Targeted Drug Delivery
edited by Angela K. Dillow and M. Lowman
679 pages • $238.95 + shipping

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