Biological Concepts and Techniques in Toxicology presents how current scientific applications and methods impact and revolutionize mainstream toxicological research.
This expertly conveived guide explores toxicological issues of particualr world intrest, such as toxicity of nanomaterials, military jet fuels, and genetically-modified foods.
Biological Concepts and Techniques in Toxicology:
- highlights new methods nad concepts that may have a mjor impact on the field of toxicology in years to come
- presents a concise overview of hormesis and shows its impact on the interpretation of dose-response relationships
- demonstrates how biolgoical data and test systems are applied to toxicology practices
- reviews current applications in nanomaterials, forenscis, and pharmaceutics
- provides and extensive reivew of developments in toxicokinetics
Contents
New Concepts and Approaches
- Toxicogenomics: Gene Expression Analysis and Computational Tools
- Proteomics
- The Potential of Metabonomics in Toxicology
- Quantitative Structure-Toxicity Relationships Using Chemodescriptors and Biodescriptors
- Hormesis: A Key Concept in Toxicology
Integration Into Practice
- Chemical Risk Assessment
- Toxicokinetics: Fundamentals and Applications in Drug Development and Safety Assessment
- Validation of In Vitro Methods for Toxicology Studies
- Chemical Mixtures Risk Assessment and Technological Advances
Examples Applied to Problems
- Risk-Based Approach to Foods Derived for Genetically Engineered Animals
- Toxicology of Nanomaterials
- The Biological Basis of Experimental Toxicity of Jet Propulsion Fuel-8
- Drug Safety Toxicology
- Statins and Toxicity
- Inhalation Toxicology
- Modern Gas Chromatography/Mass Spectrometry in Human Forensic Toxicology
Index
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