Chiral Separation Techniques covers all the approaches highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.

Contents

1. Method Development and Optimization of Enantioseparations Using Macrocyclic Glycopeptide Chiral Stationary Phases
2. Role of Polysaccharides in Chiral Separations by Liquid Chromatography and Capillary Electrophoresis
3. Analytical and Preparative Potential of Immobilized Polysaccharide-Derived Chiral Stationary Phases
4. Chiral Separations Using Supercritical Fluid Chromatography
5. Chiral Separation by Ligand Exchange
6. Advances in Simulated Moving Bed Chromatographic Separations
7. Less Common Applications of Enantioselective HPLC Using the SMB Technology in the Pharmaceutical Industry
8. Enantiomer Separation by Chiral Crown Ether Stationary Phases
9. Enantioselective Separation of Amino Acids and Hydroxy Acids by Ligand Exchange with Copper(II) Complexes in HPLC (Chiral Eluent) and in Fast Sensing Systems
10. Enantiometer Separation by Capillary Electrophoresis
11. Counter-current Chromatography in the Separation of Enantiometers
12. Separation of Enantiometers Using Molecularly Imprinted Polymers
13. Enantioselective Biosensors
14. Chiral Analysis in Capillary Electrochromatography (CEC) and CEC Coupled to Mass Spectrometry
15. Chiral Analysis Using Polymeric Surfactants in Micellar Electrokinetic Chromatography (MEKC) and MEKC Coupled to Mass Spectrometry
16. Polarimeter Chiral Detectors in Enantioseparations
17. Preparative Chiral Chromatography - a Powerful and Efficient Tool in Drug Discovery

Index

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