Chromatographic Methods in Clinical Chemistry and Toxicology aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts.
Features:
- Focuses almost exclusively on clinical relevance and applications
- Devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text
Contents
Quality Assurance, Quality Control and Method Validation in Chromatographic Applications
- Definition of Quality Assurance and Quality Control
- Professional Organizations
- Internal Quality Assurance and Control
- External Quality Assurance
Liquid Chromatographic-Mass Spectrometric Measurement of Anabolic Steroids
- LC-MS Analysis of Synthetic Steroids or Animal Samples
- LC-MS Analysis of Natural Androgens in Human Samples
High-performance Liquid Chromatography in the Analysis of Active Ingredients in Herbal Nutritional Supplements
- St John’s Wort
- Herbal Supplements with Digoxin-like Immunoreactivity
- Herbal Remedies and Abnormal Liver Function Tests
- Ginkgo Biloba
- Echinacea
- Valerian
- Feverfew
- Garlic
- Ephedra (Ma Huang) and Related Drugs
Measurement of Plasma L-DOPA and L-Tyrosine by High-Performance Liquid Chromatography as a Tumor Marker in Melanoma
- Melanogenesis
- L-DOPA Alone
- L-DOPA/L-Tyrosine Ratio
Hypersensitive Measurement of Proteins by Capillary Isoelectric Focusing and Liquid Chromatography-Mass Spectrometry
- A Robust CIEF-RPLC Interface
- First-Generation CIEF-RPLC-MS System for Proteins
- Second-Generation CIEF-RPLC-MS System
Chromatographic Measurement of Transferrin Glycoforms for Detecting Alcohol Abuse and Congenital Disorders of Glycosylation
- Transferrin Microheterogeneity
- Carbohydrate-deficient Transferrin (CDT)
- Congenital Disorders of Glycosylation (CDG)
- Analytical Methods for Transferrin Microheterogeneity
- Chromatographic Methods for CDT
- Chromatographic Methods for CDG
Chromatographic Measurements of Catecholamines and Metanephrines
- Total or individual assays
- Analytical Measurements of Catecholamines and Metanephrines
- Early Methods
- Current Chromatographic Methods
- Practical Considerations for the Stability of Urinary Catecholamines and Metanephrines During Storage
Chromatographic Measurement of Volatile Organic Compounds (VOCs)
- Intended Use
- Volatility of Compounds
- Sample Collection, Handling and Storage
- Headspace Gas Chromatographic Methods
- Columns and Detectors
- Identification, Quantitation and Confirmation
- Ethanol and Other Volatile Alcohols
- Inhalants and Screening for Multiple VOCs
- Interpretation
Chromatographic Techniques for Measuring Organophosphorus Pesticides
- Organophosphorus Pesticides (OPs)
Chromatographic Analysis of Nerve Agents
- Neuromuscular Blockers
- Paralytic Shellfish Poisoning: Saxitoxin
History and Pharmacology of c-Hydroxybutyric Acid
- History of Illicit Use of GHB
- Clinical Use of GHB in Humans
- History of Illicit Use of GBL and 1,4BD
- Distribution and Pharmacokinetics of GHB, GBL and 1,4BD
- GHB Interpretation Issues and Post-mortem Production
- Analysis for GHB, GBL and 1,4BD
Liquid Chromatography with Inductively Coupled Plasma Mass Spectrometric Detection for Element Speciation: Clinical and Toxicological Applications
- Liquid Chromatography with Inductively Coupled Plasma Mass Spectrometric Detection
- Analytical Applications of Clinical and Toxicological Relevance
Applications of Gas Chromatography-Mass Spectrometry to the Determination of Toxic Metals
Index
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