Wintrobe's Clinical Hematology continues its tradition of excellence in correlating basic science with the clinical practice of hematology.

Wintrobe's Clinical Hematology is the most comprehensive hematology book on the market and is organized to help physicians find clinical answers quickly and easily.

The Eleventh Edition places a greater emphasis on clinical hematology, especially molecular aspects and new therapies.

Most chapters have been revised or reconfigured, and seven new chapters have been added: Gene Therapy, Congenital Immunodeficiency Syndromes, Acute Lymphocytic Leukemia in Adults, Acute Myelogenous Leukemia in Children, Acute Promyelocytic Leukemia, Systemic Mastocytosis, and Diagnosis and Classification of Lymphoproliferative Disorders.

Contents:

1. Examination of the Blood and Bone Marrow
2. Clusters of Differentiation
3. Clinical Flow Cytometry
4. Cytogenetics
5. Molecular Biology and Hematology
6. Origin and Development of Blood Cells
7. Erythropoiesis
8. The Mature Erythrocyte
9. Destruction of Erythrocytes
10. Neutrophilic Leukocytes
11. The Human Eosinophil
12. Basophilic Leukocytes: Mast Cells and Basophils
13. Mononuclear Phagocytes
14. Phagocytosis
15. Lymphocytes and Lymphatic Organs
16. B Lymphocytes
17. T Lymphocytes and Natural Killer Cells
18. Effector Mechanisms in Immunity
19. Megakaryocytes and Platelets
20. Platelet Function in Hemostasis and Thrombosis
21. Blood Coagulation and Fibrinolysis
22. Endothelium: Angiogenesis and the Regulation of Hemostasis
23. Red Cell, Platelet, and White Cell Antigens
24. Transfusion Medicine
25. Hematopoietic Stem Cell Transplantation
26. Gene Therapy for Hematologic Disorders, Human Immunodeficiency Virus Infection, and Cancer
27. Anemia: General Considerations
28. Iron Deficiency and Related Disorders
29. Sideroblastic Anemias
30. Hemochromatosis
31. Porphyria
32. Hereditary Spherocytosis and Other Anemias Due to Abnormalities of the Red Cell Membrane
33. Hereditary Hemolytic Anemias Due to Enzyme Disorders
34. Mechanisms of Immune Destruction of Erythrocytes
35. Autoimmune Hemolytic Anemias
36. Alloimmune Hemolytic Disease of the Fetus and Newborn
37. Paroxysmal Nocturnal Hemoglobinuria
38. Acquired Nonimmune Hemolytic Disorders
39. Abnormal Hemoglobins: General Principles
40. Sickle Cell Anemia and Other Sickling Syndromes
41. Unstable Hemoglobin Disease
42. Thalassemias and Related Disorders: Quantitative Disorders of Hemoglobin Synthesis
43. Megaloblastic Anemias: Disorders of Impaired DNA Synthesis
44. Acquired and Inherited Aplastic Anemia Syndromes
45. Red Cell Aplasia
46. Congenital Dyserythropoietic Anemias
47. Anemias Secondary to Chronic Disease and Systemic Disorders
48. Anemias Unique to Pregnancy and the Perinatal Period
49. Hemoglobins Associated with Cyanosis: Methemoglobinemia and Low-Affinity Hemoglobins
50. Erythrocytosis
51. Diagnostic Approach to the Bleeding Disorders
52. Thrombocytopenia: Pathophysiology and Classification
53. Thrombocytopenia Caused by Immunologic Platelet Destruction
54. Thrombotic Thrombocytopenic Purpura and Other Forms of Nonimmunologic Platelet Destruction
55. Miscellaneous Causes of Thrombocytopenia
56. Bleeding Disorders Caused by Vascular Abnormalities
57. Thrombocytosis
58. Qualitative Disorders of Platelet Function
59. Inherited Coagulation Disorders
60. Acquired Coagulation Disorders
61. Thrombosis and Antithrombotic Therapy
62. Diagnostic Approach to Malignant and Nonmalignant Disorders of the Phagocytic and Immune Systems
63. Neutropenia
64. Qualitative Disorders of Leukocytes
65. Abnormalities of the Monocyte-Macrophage System: Lysosomal Storage Diseases
66. Langerhans Cell Histiocytosis
67. Infectious Mononucleosis and Other Epstein-Barr Virus-Related Disorders
68. Primary Immunodeficiency Syndromes
69. Acquired Immunodeficiency Syndrome
70. Disorders of the Spleen
71. Hematopoietic-Lymphoid Neoplasms: Principles of Diagnosis
72. Complications of Hematopoietic Neoplasms
73. Principles and Pharmacology of Chemotherapy
74. Immunotherapy
75. Supportive Care in Hematologic Malignancies
76. Molecular Genetics of Acute Leukemia
77. Classification and Differentiation of the Acute Leukemias
78. Acute Lymphoblastic Leukemia in Adults
79. Acute Myeloid Leukemia in Adults
80. Acute Lymphoblastic Leukemia in Children
81. Acute Myelogenous Leukemia in Children
82. Acute Promyelocytic Leukemia
83. Myelodysplastic Syndromes
84. Chronic Myeloid Leukemia
85. Polycythemia Vera
86. Myelofibrosis
87. Systemic Mastocytosis
88. Diagnosis and Classification of Non-Hodgkin Lymphomas
89. Molecular Aspects of Non-Hodgkin Lymphomagenesis
90. Non-Hodgkin Lymphomas in Adults
91. Non-Hodgkin Lymphomas in Children
92. Chronic Lymphocytic Leukemia
93. Hairy Cell Leukemia
94. Cutaneous T-Cell Lymphomas: Mycosis Fungoides and Sezary Syndrome
95. Hodgkin Disease
96. Practical Aspects of the Clinical Approach to Patients with Monoclonal Immunoglobulin Disorders
97. Monoclonal Gammopathy of Undertermined Significance and Smoldering Multiple Myeloma
98. Multiple Myeloma
99. Immunoglobulin Light-Chain Amyloidosis (Primary Amyloidosis)
100. Waldenstrom Macroglobulinemia
101. Cryoglobulinemia, Heavy Chain Diseases, and Monoclonal Gammopathy-Associated Disorders

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