Degenerative Disc Disease offers practical advice on when to operate and when to treat conservatively and provides complete information on alternatives to surgery and surgical options.

Degenerative Disc Disease is a comprehensive, up-to-date reference on degenerative disc disease.

Contents

Basics

1. Is There Such a Thing as Degenerative Disc Disease?
2. Morphologic Changes of Endplates in Degenerative Disc Disease
3. Biochemical Changes in Degenerative Disc Disease
4. The Physiology of Intervertebral Disc Degeneration
5. Degenerative Disc Disease and Occupational Exposure
6. Disc Degeneration and Segmental Instability
7. Internal Disc Disruption

Diagnosis

8. Imaging of Degenerative Disc Disease
9. Behavior of the Disc in Upright Magnetic Resonance Imaging
10. Lumbar Discography

Clinical Presentation

11. Disc Degeneration and Low Back Pain
12. Disc Degeneration in Children and Adolescents

Conservative Treatment Modalities

13. Gene Therapy Approach for the Treatment of Disc Degeneration

Biologic Aspects of Surgical Fusion

14. Bone Graft Alternatives in Spinal Surgery
15. Inducing Spine Fusion with Osteoinductive Molecules

Surgical Treatment Modalities

16. Intradiscal Electrothermal Therapy
17. Anterior Lumbar Interbody Fusion Versus Posterior Lumbar Interbody Fusion for Degenerative Disc Disease
18. Posterolateral Fusion
19. A New Concept in Spinal Stabilization: OptiMesh
20. The Graf Ligament System
21. Characterization of a Synthetic Bioactive Spinal Interbody Device
22. K-Centrum, a "Zero-Profile" Anterior Spinal Intramedullary Rod Fixation System: Preclinical Testing and Clinical Experience
23. Dynamic Neutralization System for the Spine in Degenerative Disc Disease
24. Cervical Interbody Fusion with a New Composite in Degenerative Disc Disease: A Preliminary Experience

Disc Replacements: Total Disc Replacements

25. Ten Years On
26. Total Disc Replacement for Low Back Pain of Discogenic Origin
27. The PDN Prosthetic Disc Nucleus Device: Product Design and Clinical Results

Economic and Ethical Considerations

28. The Evidence Base for Treatment of - not Degenerative Disc Disease - but Back Pain
29. The Need for Central Registration: Spine Tango, A European Spine Registry
30. Assessment of Health-Related Quality of Life
31. Rationale for the Surgical Treatment of Degenerative Disc Disease from the Cochrane Review
32. Animal Models in the Study of Degenerative Disc Disease
33. Epidemiology, Outcome, and Costs of Surgery for Lumbar Disc Herniation
34. Clinical Outcome, Measurements, and Languages: Some Cultural Aspects

Index

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