Diseases of the Breast is completely revised and updated, with 24 brand-new chapters
Diseases of the Breast, Third Edition is a must for all clinicians who treat benign or malignant breast diseases.
This edition features two new sections on pathology, biological markers, and staging of breast cancer and adjuvant systemic therapy of primary breast cancer.
Other new chapters cover imaging, pathogenesis of breast cancer, special therapeutic problems, and breast cancer in young women.
Treatment-oriented chapters have been reorganized for greater depth of coverage.
An up-to-the-minute “late-breaking” page has been added to many chapters just before publication.
Diseases of the Breast also includes new full-color pathology illustrations.
Contents:
- Sect. I Breast anatomy and development
- Breast anatomy and development
- Molecular mechanisms regulating breast development
- Sect. II Diagnosis and management of benign breast diseases
- Physical examination of the breast
- Management of the palpable breast mass
- Management of disorders of the ductal system and infections
- Management of breast pain
- Abnormalities of the breast in pregnancy and lactation
- Management of gynecomastia
- Pathology of benign breast disorders
- Sect. III Breast imaging and image-guided biopsy techniques
- Screening for breast cancer
- Imaging analysis : mammography
- Imaging analysis : ultrasonographic imaging
- Imaging analysis : magnetic resonance imaging
- Imaging : new techniques
- Image-guided biopsy of nonpalpable breast lesions
- Sect. IV Epidemiology and assessing and managing risk
- Nongenetic factors in the causation of breast cancer
- Inherited genetic factors and breast cancer
- Newer techniques of risk assessment
- Evaluation and management of women with a strong family history
- Chemoprevention of breast cancer : laboratory principles
- Chemoprevention : clinical aspects
- Sect. V Pathogenesis of breast cancer
- Genomic events in breast cancer progression
- Targeted therapeutics in breast cancer : challenges to success
- Alterations in the ErbB signaling network in breast cancer
- The role of proteomic analyses in breast cancer
- Microarray analysis of human breast cancer
- The biology of breast tumor angiogenesis
- Control of invasion and metastasis
- The Bcl-2 family proteins, apoptosis, and breast cancer
- Sect. VI In situ carcinoma
- Lobular carcinoma in situ : biology and pathology
- Lobular carcinoma in situ : clinical management
- Biologic features of human premalignant breast disease
- Ductal carcinoma in situ and microinvasive carcinoma
- Sect. VII Pathology, markers, and staging of invasive breast cancer
- Pathology of invasive breast cancer
- The biology of estrogen receptors
- Clinical aspects of estrogen and progesterone receptors
- Impact of Her-2/neu expression on natural history and outcome of human breast cancer
- Staging of breast cancer
- Evaluation of patients for metastasis prior to primary therapy
- Prognostic and predictive markers
- Bone marrow micrometastases and circulating tumor cells
- Lymph node micrometastases
- Sect. VIII Local treatment of primary invasive breast cancer
- Local management of invasive cancer : breast
- Local management of invasive breast cancer : axilla
- Postmastectomy radiation therapy
- Breast reconstruction
- Techniques in surgery : lumpectomy for palpable and nonpalpable cancer
- Techniques in surgery : sentinel node biopsy and axillary dissection
- Techniques in surgery : therapeutic and prophylactic mastectomy
- Techniques in surgery : prophylactic oophorectomy
- Techniques in radiation therapy after lumpectomy
- Management summary on local therapy
- Sect. IX Adjuvant systemic therapy of primary breast cancer
- Adjuvant endocrine therapy
- Adjuvant chemotherapy and chemoendocrine therapy
- Bone metastases from breast cancer : the role of bisphosphonates in prevention
- Preoperative therapy for operable breast cancer
- Adjuvant systemic therapy treatment guidelines
- Sect. X Special therapeutic problems
- Locally advanced breast cancer
- Inflammatory breast cancer
- Male breast cancer
- Phyllodes tumors
- Paget's disease
- Rare cancers in the breast
- Pregnancy-associated breast cancer and subsequent pregnancy in breast cancer survivors
- Occult primary cancer with axillary metastases
- Sect. XI Evaluation after primary therapy and management of recurrent breast cancer
- Evaluation of patients after primary therapy
- Local-regional recurrence after breast conservation treatment or mastectomy
- Treatment of metastatic breast cancer : the role of Herceptin
- Treatment of metastatic breast cancer
- Sect. XII New breast cancer therapeutic approaches
- Angiogenesis inhibition in breast cancer
- Immunology and immunotherapy
- Tyrosine kinase inhibitors
- Sect. XIII Site-specific therapy of metastatic breast cancer
- Brain metastases
- Epidural metastases
- Leptomeningeal metastases
- Brachial plexopathy in patients with breast cancer
- Ocular metastases
- Malignant effusions
- Management of discrete pulmonary nodules
- Management of isolated liver metastases
- Biology of bone metastases
- Bisphosphonates and other medical treatment of bone metastases
- Local treatment of bone metastases
- Sect. XIV Breast cancer in special populations
- Breast cancer in older women
- Breast cancer in young women
- Breast cancer in minority women
- End-of-life considerations in patients with breast cancer
- Sect. XV Issues in breast cancer survivorship
- Nursing care in patient management and quality of life
- Preserving and restoring function in breast cancer survivors
- Issues in breast cancer survivorship
- Lymphedema
- Management of menopausal problems in breast cancer survivors
- Reproductive health in breast cancer patients
- Sect. XVI Other considerations
- Medical legal aspects of breast cancer evaluation and management
- Cost and cost-effectiveness considerations
Appendix: Recent and ongoing randomized trials of adjuvant therapy for breast cancer, classified by research organization
Index
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