The premier clinical hepatology reference for 50 years, Schiff's Diseases of the Liver is in its Tenth Edition—now in full color throughout.

The first third of the book covers anatomy, pathology, testing, imaging, and effects of liver disease on other organs. Subsequent sections address specific diseases and clinical syndromes. Each of the 12 sections begins with an overview, and each chapter starts with an outline of key concepts. Numerous clinical algorithms appear throughout the text.

Features:

• Now full-colour throughout
• Major new transplant section, focusing not on surgery but on pre-transplant and post-transplant evaluation and management
• Updates on key topics such as hepatitis, NASH, drug-induced pathologies
• Section overviews begin each of the 12 sections
• Key Concepts outlines start chapters
• Treatment guidelines and management algorithms

Contents

Volume One

Overview: Clinical Fundamentals of Hepatology

1. History taking and physical examination for the patient with liver disease
2. Laboratory tests
3. Liver biopsy and laparoscopy
4. Imaging
5. Interventional radiology procedures for diagnosis and treatment of hepatobiliary disease
6. Endoscopic retrograde cholangiopancreatography

General Considerations

7. Physioanatomic considerations
8. Bilirubin metabolism and jaundice
9. Hepatic histopathology
10. Mechanisms of liver injury
11. The liver in systemic disease
12. Hematologic disorders and the liver
13. Nutrition and the liver

Consequences of Liver Disease

14. Hepatic fibrosis
15. Portal hypertension and nonsurgical management
16. Surgical management of portal hypertension
17. Renal complications and hepatorenal syndrome
18. Pulmonary manifestations of liver disease
19. Ascites and spontaneous bacterial peritonitis
20. Hepatic encephalopathy
21. Fulminant hepatic failure

Cholestatic Disorders

22. Gallstone disease: pathogenesis and treatment
23. Primary sclerosing cholangitis
24. Primary biliary cirrhosis
25. Postoperative jaundice

Viral Hepatitis

26. The hepatitis viruses
27. Hepatitis A
28. Hepatitis E
29. Hepatitis B and D
30. Hepatitis C
31. Autoimmune hepatitis

Volume Two

Alcohol and Drug-Induced Disease

32. Alcoholic liver disease
33. Drug-induced liver disease
34. Mechanisms of drug-induced liver injury

Genetics and Metabolic Disease

35. Wilson disease
36. Hemochromatosis and iron storage disorders
37. α₁-Antitrypsin deficiency
38. Porphyrias
39. Nonalcoholic fatty liver disease

Vascular Diseases of the Liver

40. Vascular diseases of the liver
41. The liver in circulatory failure

Benign and Malignant Tumors: Cystic Disorders

42. Benign solid tumors
43. Nodular and cystic lesions
44. Hepatocellular carcinoma
45. Surgical options for the treatment of hepatocellular carcinoma

The Liver in Pregnancy and Childhood

46. The liver in pregnancy
47. Liver disease in infancy and childhook

Infectious and Granulomatous Disease

48. Liver abscesses
49. Parasitic diseases
50. Bacterial and systemic infections
51. Hepatobiliary manifestations of human immunodeficiency virus
52. Granulomas of the liver

Elements of Liver Transplantation

53. Selection and timing of liver transplantation
54. Immunosuppression: the global picture
55. The first six months following liver transplantation
56. The long-term care of transplanted patient
57. The surgical options of liver transplantation
58. Recurrent disease following liver transplantation
59. The role of retransplantation
60. Hepatobiliary complications of hematopoietic cell transplantation

Index

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