Diseases of the Pancreas is based on the latest comprehensive data about molecular mechanism of acute pancreatitis, chronic pancreatitis and pancreatic cancer.

The diagnostic techniques including histology, radiology, sonography etc. are based on the sensitivity and specificity of the respective methods.

Special focus is given to the indication and contraindication to surgical techniques.

The book contains specific treatment modality and results for the first time after long-term outcome evaluation. Surgical techniques are displayed with colored sketches series.

Contents

Section 1: Anatomy of the Pancreas

1. Development of the Pancreas and Response to Disease
2. Congenital Anomalies of the Pancreas and the Extrahepatic Bile Ducts
3. Surgical Vascular Anatomy and Histology

Section 2: Physiology and Pathophysiology of the Pancreatic Functions

4. Pancreatic Exocrine Secretion
5. Physiology and Pathophysiology of Endocrine Pancreatic Secretion
6. Sphincter of Oddi Physiology and Pathophysiology

Section 3: Clinical Standards of Diagnostic Measures

7. Ultrasound
8. Contrast-Enhanced CT and MRI
9. Endoscopic Retrograde Cholangiopancreatography
10. Fine-Needle Aspiration Biopsy of the Pancreas
11. FDG-PET and PET/CT in Pancreatic Cancer
12. Laboratory Diagnosis of Exocrine and Endocrine Dysfunctions in Inflammatory and Neoplastic Lesions
13. Guidelines, Clinical Evaluation, Short Track

Section 4: Acute Pancreatitis

14. Etiology and Epidemiology of Acute Pancreatitis
15. Epidemiology and Intervention During the Clinical Course of Biliary Acute Pancreatitis
16. Pathogenesis and Pathophysiology of Acute Pancreatitis
17. Natural Course of Acute Pancreatitis
18. Classification of Severe Acute Pancreatitis
19. 1. Biochemical Diagnosis, Staging, and Prediction
    2. Imaging Diagnosis of Acute Pancreatitis
20. Nonsurgical Management of Acute Pancreatitis
21. 1. Indications for the Surgical Management of Necrotizing Pancreatitis
    2. Debridement and Closed Packing for the Treatment of Necrotizing Pancreatitis
    3. Necrosectomy and Redressing
    4. Necrosectomy and Closed Lavage
    5. Infected Necrosis – Minimally Invasive Necrosectomy
    6. Benefits and Limitations of Necrosectomy
22. Surgical Management of Pancreatic Abscess
23. Surgical Management of Pseudocysts after Acute Pancreatitis
24. Interventional Management of Pancreatic Fluid Collections and Abscesses
25. Pancreatic and Intestinal Fistulas
26. Late Outcome after Necrosectomy

Section 5: Chronic Pancreatitis

27. Mechanisms of Pain in Chronic Pancreatitis
28. Natural Course of Chronic Pancreatitis
29. Chronic Pancreatitis: Inflammatory Mass in the Head of the Pancreas – Pacemaker of Chronic Pancreatitis
30. Diagnosis: Functional Testing, Radiological Work-up of Chronic Pancreatitis
31. Medical Management of Chronic Pancreatitis
32. Tropical Chronic Pancreatitis
33. Hereditary Chronic Pancreatitis: Diagnosis and Management
34. Endoscopic Interventional Treatment
35. Indication for Surgical Treatment in Chronic Pancreatitis
36. Pancreatic Duct Drainage Procedures
37. Duodenum-Preserving Pancreatic Head Resection
38. Pancreaticoduodenctomy for Chronic Pancreatitis – With or Without Pylorus Preservation
39. Central Pancreatectomy
40. Distal Pancreatectomy in Patients with Chronic Pancreatitis
41. Total Pancreatectomy
42. Surgical Treatment of Pseudocysts in Chronic Pancreatitis
43. Late Outcome After Medical and Surgical Treatment of Chronic Pancreatitis

Section 6: Pancreatic Cancer

44. Epidemiology of Pancreatic Cancer
45. Pathology of Pancreatic Cancer
46. Genetic Pathways in Pancreatic Tumorigenesis
47. The Clinical Assessment of Pancreatic Cancer
48. The Staging of Pancreatic Cancer
49. Oncological Management of Pancreatic Cancer in Advanced Stages
50. Indications for Resection of Pancreatic Cancer
51. The Kausch-Whipple Pancreatectomy
52. Pylorus-Preserving Pancreaticoduodenectomy

Index

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