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Disinfection, Sterilization, and Preservation
The Essentials
Fifth edition
edited by Seymour S. Block
Now in its thoroughly revised, updated Fifth Edition, Disinfection, Sterilization, and Preservation is a comprehensive, practical reference on contemporary methods of disinfection, sterilization, and preservation and their medical, surgical, and public health applications. More than a third of this edition's chapters cover subjects never addressed in previous editions.
New topics covered include:
- recently identified pathogens
- microbial biofilms
- use of antibiotics as antiseptics
- synergism between chemical microbicides
- pulsed-light sterilization of pharmaceuticals
- new methods for medical waste management
Close attention is given to infection control problems posed by endoscopes, implants, prostheses, and organ transplantation and to prevention of opportunistic infections in immunocompromised patients.
Contents
Introduction
- Historical review
- Definition of terms
Fundamental Principles of Activity
- Principles of antimicrobial activity and resistance
- Physical factors influencing the activity of antimicrobial agents
- Kinetics of the inactivation of microorganisms
- Principles of the thermal destruction of microorganisms
Sterilants, Disinfectants, and Antiseptics—A: By Chemical Type
- Chlorine and chlorine compounds
- Iodine and iodine compounds
- Peroxygen compounds
- Disinfection and sterilization using ozone
- Chlorine dioxide
- Alcohols
- Phenolic compounds
- Surface-active agents
- Chlorhexidine
- Gaseous chemical sterilization
- Glutaraldehyde
- Nitrogen compounds
- Use of metals as microbicides in preventing infections in healthcare
- New and developing chemical antimicrobials
- Antiobiotics used as disinfectants and antiseptics
- Synergism in disinfectant formulation
- Formulation of sanitizers and disinfectants
Sterilants, Disinfectants, and Antiseptics—B: Type of Microorganism
- Control of Staphylococcus aureus and enterococcal infections
- Control of Legionells
- Mycobacterial disinfection
- Chemical sporicidal and sporostatic agents
- Principles of viral control and transmission
- Human immunodeficiency virus: disinfection and control
- Measures for disinfection and control of viral hepatitis
- Fungistatic and fungicidal compounds for human pathogens
- Antiprotozoan and anthelmintic agents
- Prions
- Microbial biofilms: prevention, control, and removal
- Emerging infectious diseases
Physical Sterilization and Disinfection
- Sterilization by heat
- Sterilization and preservation by radiation sterilization
- Sterilization processes utilizing low-temperature plasma
- Pulsed-light disinfection of water and sterilization of blow/fill/seal manufactured aseptic pharmaceutical products
- Sterile filtration of liquids and gases
- Disinfection by ultraviolet irradiation
- Development of nonthermal methods for microbial control
Medical and Health-Related Applications
- Chemical disinfection of medical and surgical materials
- Surgical antisepsis
- Practical applications in infection control
- Epidemiology and prevention of nosocomial infections
- Medical device infections
- Infection control with endoscopes
- Medical applications of peracetic acid
- Infection prevention for skin and burns
- Aseptic and antiseptic treatment of donated and living engineered organs and tissues
- Disinfection of water: drinking water, recreational water, and wastewater
- Sterilization, disinfection, and asepsis in dentistry
- Disinfection and disease prevention in veterinary medicine
- Disinfection of contact lenses
- Hazard of infectious agents in microbiologic laboratories
- An overview of facilities for the control of microbial agents
- Infectious wastes: efficient and effective management
Miscellaneous Topics
- Protection against biological warfare agents
- Food- and water-infective microorganisms
- Prevention of infection from food and water
- Chemical disinfection of microbial contaminants on surfaces
- Survival of microorganisms in the environment
- Microorganisms and building-related illnesses
- Preservation and microbiological attributes of nonsterile pharmaceutical products
- Regulation of antimicrobial presicides in the United States
- Federal regulation of liquid chemical germicides by the U.S. Food and Drug Administration
Methods of Testing
- Methods of testing disinfectants
- Methods of testing oral and topical antiseptics and antimicrobials
- Sterility testing: validation of sterilization processes and sporicide testing
- Methods of testing sanitizers and bacteriostatic substances
- Methods of testing fungicides
- Methods of testing the virucidal activity of chemicals
- Methods of testing protozoacides and antihelmintics
- Biocide susceptibility testing of biofilms
Index
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Disinfection, Sterilization, and Preservation
The Essentials
Fifth edition
edited by Seymour S. Block
1,488 pages • $278.00 + shipping
Texas residents please add 6.75 % sales tax
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