edited by
Elena V. Grigorenko

• Presents new techniques involved in the usage of high density cDNA and oligonucleotide arrays and their applications
• Includes detailed protocols for large scale analysis of gene expression
• Contains works from leaders in their respective fields
• Presents methods that are adaptable to various laboratory conditions

DNA Arrays: Technologies and Experimental Strategies offers a view of different aspects of this rapidly developing technology, including oligonucleotide and electrochemical arrays.

Distinguished investigators from academia and industry provide expert insight into methodological fundamentals of construction of DNA arrays, optimization of hybridization conditions, the use of expression data in bioinformatics, different software tools, and the application of microarray technology for drug discovery process.

Contents

1. Introduction
2. Technology Development for DNA Chips
3. Experimental Design for Hybridization Aray Analysis of Gene Expression
4. Nylon Platform: Pros and Cons
5. Oligonucleotide Array Technologies for Gene Expression Profiling
6. Electrochemical Detection of Nucleic Acids
7. DNA Microarrays in Neurobiology
8. Data Management in Microarray Fabrication, Image Processing and Data Mining
9. Zeroing In on Essential Gene Expression Data
10. Application of Arrayed Libraries for Analysis of Differential Gene Expression Followed Chronic Cannabinoid Exposure

Supplier List
List of Web Sites Related to DNA Arrays
Index

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