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Drug Delivery book from C.H.I.P.S.

Drug Delivery
Principles and Applications
edited by Binghe Wang
Teruna Siahaan
Richard A. Soltero

Drug Delivery: Principles and Applications is an indispensable tool for those working at the front lines of new drug development.

Written for busy professionals at the forefront of new drug development, Drug Delivery: Principles and Applications gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery.

Drug Delivery: Principles and Applications covers the entire field in a systematic but concise way. It begins with an in-depth review of key fundamentals, such as physiochemical and biological barriers; drug delivery pathways; metabolism; drug formulation; pharmacokinetic and pharmacodynamic issues; and more. The remainder of the book is devoted to the systematic examination-including overviews, timely examples, and extensive references-of a host of specific subjects, including:

  • Receptor-mediated drug delivery
  • Prodrug delivery approaches
  • Oral protein and peptide drug delivery
  • Gene therapy and gene delivery
  • Ultrasound-mediated drug delivery
  • Polycationic peptides and proteins in drug delivery
  • Pulmonary drug delivery
  • Antibody-directed drug delivery
  • Efflux transporters in drug excretion
  • Intellectual property issues in drug delivery

Contents

  1. Factors that Impact the Developability of Drug Candidates-An Overview
  2. Chemical, Biochemical, and Physiological Barriers to Oral Drug Delivery
  3. Pathways for Drug Delivery to the Central Nervous System
  4. Physiochemical Properties, Formulation and Drug Delivery
  5. Targeted Bioavailability: A Fresh Look at Pharmacokinetic and Pharmacodynamic Issues in Drug Delivery
  6. Pre-Systemic and First-pass Metabolism
  7. Cell Culture Models for Drug transport Studies
  8. Prodrug Approaches to Drug Delivery
  9. Receptor-mediated Drug Delivery
  10. Oral Protein and Peptide Drug Delivery
  11. Metabolic Activation and Drug Targeting
  12. Ultrasound Mediated Drug Delivery
  13. Polycationic Peptides and Proteins in Drug Delivery: Focus on Non-Classical Transport
  14. Gene Therapy and Gene Delivery
  15. Parenteral Formulations for Peptide and Protein Delivery, and Monoclone Antibody Drugs
  16. Pulmonary Drug Delivery – Pharmaceutical Chemistry and Aerosol Technology
  17. Antibody-Directed Drug Delivery
  18. Efflux Transporters in Drug Excretion
  19. Liposome as Drug Delivery Vehicles
  20. Regulatory and IP Issues in Drug Delivery Research

Index

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Drug Delivery
Principles and Applications
edited by Binghe Wang, Teruna Siahaan,
and Richard A. Soltero

2005 • 448 pages • $115.95 + shipping
Texas residents please add 6.75 % sales tax

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