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Pharmaceutical book from C.H.I.P.S.

Drug Testing In Vitro
Breakthroughs and Trends in Cell Culture Technology
by Uwe Marx

Drug Testing In Vitro provides an overview of the main areas of progress involving target finding and validation with molecular biology, and in-vitro testing of drug safety to the production of biological molecules.

Contents

Emerging In-Vitro Culture Technologies

  • An Overview on Bioreactor Design, Prototyping and Process Control for Reproducible Three-Dimensional Tissue Culture
  • An Overview on Bioelectronic and Biosensoric Microstructures Supporting High-Content Screening in Cell Cultures
  • Novel In-Vitro Exposure Techniques for Toxicity Testing and Biomonitoring of Airborne Contaminants

    Primary Tissues and Cell Lines in Drug Screening/Testing

    • Drug Screening Using Cell Lines: Cell Supply, High-Throughput and High-Content Assays
    • Cell Lines and Primary Tissues for In-Vitro Evaluation of Vaccine Efficacy
    • Designer Cells Derived from Primary Tissue and Designed Cell Lines as a Sustainable Cell Source for Drug Discovery and Safety Assessment
    • How Human Embryonic Stem Cell Research Can Impact In-Vitro Drug Screening Technologies of the Future

    The Use of Human Tissues in Drug Discovery: Scientific, Ethical, Legal, and Regulatory Environments

    • Availability, Standardization and Safety of Human Cells and Tissues for Drug Screening and Testing
    • Ethical Environment and Scientific Rationale Towards In-Vitro Alternatives to Animal Testing: Where Are We Going?

    Summary and Visions

    • How Drug Development of the 21st Century Could Benefit from Human Micro-Organoid In-Vitro Technologies

    Index

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    Drug Testing In Vitro
    Breakthroughs and Trends in Cell Culture and Technology
    by Uwe Marx

    2007 • 298 pages • $174.00 + shipping
    Texas residents please add 6.75 % sales tax
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