Epidemiology in Medicine discusses the methods of epidemiologic study design and analysis, and illustrates its discussion with many timely clinical and public health examples.
Contents
Part I: Basic Concepts
Definition and Background
- History of Epidemiology
- Changing Patterns of Mortality
- Developments in Modern Epidemiology
- The Unique Contribution of Epidemiology
Design Strategies in Epidemiologic Research
- Descriptive Studies
- Analytic Epidemiology
Statistical Association and Cause-Effect Relationships
- Evaluation of the Presence of a Valid Statistical Association
- Judgement of a Cause-Effect Relationship
- The Evalutaion of a Hypothesis: Smoking and Lung Cancer
Measures of Disease Frequency and Association
- Measures of Disease Frequency
- Measures of Association
Part II: Types of Epidemiologic Studies
Descriptive Studies
- Types of Descriptive Studies
- Hypothesis Formulation from Descriptive Studies
Case-Control Studies
- Issues in the Design and Conduct of Case-Control Studies
- Issues in Analysis
- Issues in Interpretation
Cohort Studies
- Types of Cohort Studie
- Issues in the Design and Conduct of Cohort Studies
- Issues in Analysis
- Issues in Interpretation
Intervention Studies
- Types of Intervention Studies
- Unique Problems of Intervention Studies
- Issues in the Design and Conduct of Clinical Trials
- Stopping Rules: Decision for Early Termination of a Trial
- Sample Size Considerations: Statistical Power
- Issues in Analysis and Interpretation
Part III: Description and Analysis of Epidemiologic Data
Presentation and Summarization of Data
- Types of Variables
- Data Presentation
- Summary Statistics
Analysis of Epidemiologic Studies: Evaluation the Role of Chance
- Inference
- Hypothesis Testing
- Estimation: Confidence Intervals
- Study Design Issues: Sample Size and Power
- Statistical Overviews
Analysis of Epidemiologic Studies: Evaluating the Role of Bias
- Types of Bias
- Control of Bias: Study Design
- Evaluation of the Role of Bias
Analysis of Epidemiologic Studies: Evaluating the Role of Confounding
- The Nature of Confounding
- Methods to Control Confounding in the Design
- Methods to Control Confounding in the Analysis
Part IV: Epidemiology in Disease Control
Screening
- Diseases Appropriate for Screening
- Screening Tests
- Evaluation of Screening Programs: Feasibility and Efficacy
Appendices
- Standard Statistical Tables
- Selection of an Appropriate Test of Statistical Significance
- Answers to Study Questions
Index
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