Features:
- The first comprehensive book to address this controversial issue
- Provides a definitive, up-to-date review of fetal programming
- Brings together the basic sciences and epidemiology to provide a multidisciplinary perspective
Fetal Nutrition and Adult Disease, which brings together the perspectives of leading researchers from Europe, the USA and Australasia, provides the reader with a detailed account of the evidence for and against the nutritional programming of human disease, and considers the biological basis of programming.
It addresses a topic of great current interest and consists of three sections: programming the fetus; programming human disease; and the biological basis of nutritional programming.
Contents
- Programming the Fetus
- Fetal programming of adult disease: an overview
- Nutritional basis of the fetal origins of adult disease
- Intrauterine hypoxaemia and cardiovascular development
- Programming Human Disease
- Epidemiology of the fetal origins of adult disease: cohort studies of birthweight and cardiovascular disease
- Early-life origins of adult disease: is there really an association between birthweight and chronic disease risk?
- Experimental models of hypertension and cardiovascular disease
- Associations between fetal and infant growth and non-insulin-dependent diabetes
- Programming of diabetes: experimental models
- Birthweight and the development of overweight and obesity
- Maternal nutrition in pregnancy and adiposity in offspring
- Renal disease and fetal undernutrition
- Perinatal determinants of atopic disease
- Fetal programming of immune function
- Biological Basis of Nutritional Programming
- Programming in the pre-implantation embryo
- Endocrine responses to fetal undernutrition: the growth hormone—insulin-like growth factor axis
- Impact of intrauterine exposure to glucocorticoids upon fetal development and adult pathophysiology
Index
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