Genetics of Steroid Biosynthesis and Function focuses on the genetic and cellular aspects of mammalian steroid hormones with particular attention to inherited gene lesions. With contributions from a panel of international experts, this volume provides an accessible, up-to-date overview of modern steroid biology for both the professional and novice researcher alike.

Contents

1. Steroid Biosynthesis: Enzymology, Integration and Control
2. Sterol Biosynthesis
3. Vitamin D Biosynthesis and its Disorders
4. Bile Acid Biosynthesis
5. Cholesterol Metabolism in Steroidogenic Tissues
6. Steroid 21-Hydroxylase
7. Steroid 11ß-Hydroxylase Isozymes
8. 3ß-Hydroxysteroid Dehydrogenase/ Isomerase Deficiency
9. Human 17a-Hydroxylase/17, 20-Lyase
10. Aromatase: Insights into the Roles of Estrogens Revealed by Natural and Targeted Mutations
11. 17ß-Hydroxysteroid Dehydrogenase and 5a-Reductase Deficiencies
12. Steroid Metabolism in Peripheral Tissues
13. Animal Models of Impaired Steroidgenesis
14. Regulation of Gene Expression by the Nuclear Receptor Family
15. Neurosteroids and Brain Sterols

click here to see books • videos • cd-roms of related interest