Handbook of Comparative Genomics
Principles and Methodology
by Cecilia Saccone
and Graziano Pesole

This book covers basic and applied problems in the emerging field of comparative functional genomics. It offers a comparative perspective on key principles of genome sequencing, expression, evolution, and phylogenetics in organelles, prokaryotes, model organisms, and humans.

Handbook of Comparative Genomics provides a unique and thorough treatment of biological databases, analysis of the transcriptome and proteome, and the bioinformatic approaches for comparative genome analysis. The perfect guide for students and researchers covering basic and applied problems in the emerging field of comparative functional genomics.

Features:

• Both the concepts and methodology of comparative genomics
• Reviews on the basic principles of genomics and gene expression analysis
• Bioinformatics approaches to comparative analysis
• Discussions concerning analytic methods in proteomics and transcriptomics

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SECTION I: GENOME FEATURES

• The Prokaryotic Genome
• Eukaryotes
• Organelles

SECTION II: METHODOLOGIES

• Molecular Biology Techniques for Genomics
• Biological Databases
• Computational Methods for the Analysis of Genome Sequence Data

SECTION III: COMPARATIVE GENOMICS

• Molecular Evolution
• Molecular Phylogeny

Appendix: URL's Cited in the Text
Index

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