High-Yield Immunology extracts the most important information on immunology and presents it in a concise, uncluttered fashion to prepare students for the USMLE
Contents
Overview
- Synopsis
- Concerns in Medicine
- Host-Parasite Equilibrium
- Development of the Acquired Immune System
- Clonal Selection Theory
Antigens
- Definitions
- Factors Determining Antigenicity
- Examples of Antigens
Innate Immunity
- Fundamental Characteristics
- Defensive Mechanisms
- Acute Phase Response (APR)
- Pathogen Recognition Systems
Antibodies
- General Properties
- IgG
- IgM
- IgA
- IgE
- IgD
Immunogenetics
- Genetic Control of Immunoglobin Chain Synthesis
- Genetic Control of Human Leukocyte Antigens (HLAs)
- Genetic Control of the T-Cell Antigenic Receptor (TCR)
Immunologic Assays
- Overview
- Protection Tests
- Agglutination Tests
- Precipitation Reactions
- Complement Fixation
- Fluorescent Antibody
- Western Blot
- Cell Counting and Flow Cytometry
- Reverse Transcription Polymerase Chain Reaction (RT-PCR)
- DNA Microarrays
The Immune Response
- Humoral Immunity
- Cell-Mediated Immunity (CMI)
Signal Transduction in Immune Cells
- Effective Immune Responses Require Communication Between a Wide Range of Cell Types
- Receptor Architecture and Fundamental Characteristics
- Signaling Molecules
- Pathways
Inflammation
- Introduction
- Inflammation Process
- Kinetics
- Mediators of Inflammation
Hypersensitivity Diseases
- Overview
- Anaphylaxis (Type I) Reactions
- Cell Surface Antigen-Antibody (Ag-Ab) Cytotoxicity (Type II) Reactions
- Antigen-Antibody (ag-Ab) Complex (Type III) Reactions
- Delayed-Type Hypersensitivity (Type IV) Reactions
Immunodeficiency Diseases
- Overview
- Developmental Immunodeficiency Disorders
- Acquired Immunodeficiency Syndrome (AIDS)
- Cytokine and Chemokine Deficiencies
- Senescene (Aging) of the Immune Response
Autoimmune Diorders
- Overview
- Immunoregulation Breakdown
- Systemic Autoimmune Disorders
- Organ-Specific Autoimmune Disorders
Immunologic Aspects of Transplantation
- Histocompatibility
- Complications of Organ Transplantation
- Immunosuppression
Cancer Immunology
- Definition
- Oncogenes
- Cancer and the Immune System
- Cancer Immunotherapy
Immunization
- Overview
- Specific Vaccines
- Adjuvants