Immune Dysfunction and Immunotherapy in Heart Disease is the definitive reference to the state of the science in this area.

The four parts of the book address:

• Immune Dysfunction Leading to Heart Disease: Induction by Physiological Changes
• Immune Dysfunction Promoting CVD: Induction by Transplantation Drugs
• Immune Dysfunction Leading to Heart Dysfunction: Induction or Prevention by Cardiotherapeutic Drugs
• Immune Dysfunction Leading to Heart Disease: Induction by Pathogens

Contents

Part I Immune dysfunction leading to heart disease: induction by physiological changes

1. Immunosuppression by ultraviolet light-B radiation: amediator of cardiac remodeling
2. Immune mechanisms in pediatric cardiovascular disease
3. Heart failure–role of autoimmunity
4. Immune basis of hypertension in humans
5. Immune dysregulation: potential mediator of metabolic syndrome-induced cardiac remodeling
6. T helper 2 cell cytokines in remodeling of aortic wall
7. Effects of TNF- on cardiac function
8. Immunosuppression in promotion of cardiac allograft vasculopathy
9. Immunotherapy for left ventricular dysfunction after heart transplantation

Part II Immune dysfunction promoting CVD: induction by transplantation drugs

10. Immunomodulating therapy in chronic heart failure
11. Statins in atherosclerosis: role of immune regulation
12. ACE inhibitors as immunomodulators: treatment of cardiovascular disease
13. Treatment of heart failure by anticytokine therapies

Part III Immune dysfunction leading to heart dysfunction: induction or prevention by cardiotherapeutic drugs

14. Pathogenesis of cardiovascular complications in the acquired immunodeficiency syndrome
15. Cytokines and T cell-mediated responses in autoimmune myocarditis
16. Drugs of abuse: accentuation of immunomodulation of viral myocarditis

Part IV Immune dysfunction leading to heart disease: induction by pathogens

17. Osteopontin: the link between the immune system and cardiac remodeling
18. Inflammatory immune activation in heart failure patients: therapeutic implications
19. Role of innate immune dysregulation in diabetic heart failure
20. Tolerance in heart transplantation: current and future role
21. Neutralization of Th2 cytokines in therapy of cardiovascular pathology
22. Anti-inflammatory immune therapy in heart disease
23. Cholesterol, interleukin-6 inflammation, and atherosclerosis—role of statins, bisphosphonates, and plant polyphenols in atherosclerosis and other diseases of aging
24. Autoimmune myocarditis: treatment with anti-T-cell antibodies
25. Immunosuppressive therapy to counter cardiac allograft vasculopathy
26. Role of oral pathogens in the pathogenesis of coronary heart disease
27. Myocardial regenerative potential by stem cell transplant
28. Bioflavanoids and dietary anti-inflammatory actions: role in cardiovascular diseases

Index

click here to see books • videos • cd-roms of related interest