This volume focuses on pharmaceutical biotechnology as a key area of life sciences. This book discusses crucial topics for future therapies and the cultivation of tissues and organs as well as the underlying genetics and regulatory, developmental, and biochemical networks.

Featured Topics:

• Repertoire of genomics, proteomics, cytomics, and bioinformatics
• Methods in nanotechnologies
• Degenerative and acute disease development
• Tools for target identification
• The maintenance of homeostasis and biochemical networks
• The preservation of the integrity of genetic and cellular structures

Industrial Pharmaceutical Biotechnology is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.

Contents:

1. Introduction to Functional Biotechnology
   • Scientific and Technological Foundations
   • Genomics
   • Proteomics
   • Cytomics
   • Micro-and Nanotechnology
   • Cellular Cleaning
   • Tissue Engineering (Organ Cultivation)
   • Micro-and Nanotechnologies for Medicine
   • Structural Genomics

2. Organizatorial Structures
   • Virtual and Real Enterprises
   • R&D Networks
   • Outsourcing
   • Registrations and Permissions

3. Markets and Factors
   • Products and Services
   • Economics
   • Manpower Resources

4. Biotechnology and Medicine
   • Diagnostics
   • Therapeutics
   • Gene Therapy
   • Implantates
   • Medical Devices and Technology
   • Complex Traits

5. Drug Discovery
   • Substances Derived from Bacteria, Plants, Insects, and Animals
   • Sources of Active Principles
   • Assay Systems and Models (e.g., Knock-out Mice)

6. Molecular Pharma-Biotechnology
   • Bioinformatics
   • Biological Systems and Models
   • Assay Systems
   • High-throughput Screening
   • Automation
   • Combinatorial Sythesis: Chemistry, Biology, and Biotechnology
   • Genotyping: Genetic Pre-Disposition, and Heterogeneity
   • Sequencing
   • Pharmaco-Genomics<

7. Research and Development
   • Biology, Medicine and Genetics
   • Pre-clinical and Clinical Development
   • Processes
   • Pilot Plants
   • Engineering
   • Fermentation Process Development

8. Pharmaceutical Production
   • GenePharming (Animals and Plants)
   • Vitamins
   • Amino Acids
   • Proteins
   • Antibiotics
   • Biocayalysis
   • Natural Compounds
   • Recovery/(Bio-)Processing
   • Chemical-Biotechnological Syntheses
   • Gene Therapy Vectors/Systems
   • Production: Safety, Efficacy, Consistency, and Specificity
   • Registration

9. Safety
   • Medical Safety
   • Biological Safety
   • Chemical Safety
   • Equipment Safety

10. Environment
    • Pharmaceuticals and the Environment
    • Biological Containment
    • Physical/Chemical Containment
    • Process-Integrated Environmental Protection
    • Waste/Effluent Treatment and Recycling

11. Ethics

12. Companies, Institutes, Networks, and Organizations

References
Index

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