Industrial Proteomics covers both basic elements and the state-of-the-art in applications of proteomics.

The first section gives an introduction to the field, from differential approaches to functional proteomics, including yeast two-hybrid, mass spectrometry, mapping of post-translational modifications, and NMR spectroscopy.

The second section offers a complete picture of industry studies in proteomics for human health and biotechnology applications.

The final section addresses the future, looking at the most promising areas such as protein arrays and the integration of genomic and proteomic tools.

Contents

1. Proteomics: The Basic Overview
2. Mapping Protein-Protein Interactions
3. Protein Post-Translational Modifications: Phosphorylation Site Analysis Using Mass Spectrometry
4. The Use of High Throughput Crystallography and In Silico Methods for Structure Based Drug Design
5. High Throughput Analysis of Protein Structure by H/D Exchange (H/D-Ex) Mass Spectrometry
6. Proteomics Technologies for Identification and Validation of Protein Targets
7. Proteomics Discovery of Biomarkers
8. Industrial-Scale Proteomics Analysis of Human Plasma
9. Chemical Genomics: Targets on Display
10. Bioinformatics for Proteomics
11. Protein Arrays

Index

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