by C. Vaman Rao

• Includes recently proposed concepts on immune tolerance, T-cell energy, HLA delivered peptides for immunosuppression, chemokines, the newly discovered oncogens, and much more
• Covers transplantation immunology and immune tolerance in great detail
• Provides recent information on viral strategies of immune evasion and the role of B cells in viral, bacterial, and parasitic disease
• Presents additional information on strategies for the development of vaccines against different pathogens
• Discusses recent discoveries in the factors involved in rheumatoid arthritis
• Offers many figures and tables to aid in comprehension
• Contains a glossary for quick reference

In An Introduction to Immunology, the author includes the most recent information while emphasizing the basic fundamentals of each topic so that you obtain a broad outline of the subject.

The text elucidates fundamental concepts, such as the origin of the immune system, innate and acquired immunity, and cells and organs of the immune system. It discusses recent concepts and ideas regarding innate and acquired immunity, T-cell and B-cell activation and differentiation mechanisms, factors involved in rheumatoid arthritis, T-cell clonal anergy, NK cell receptors, strategies in production of new vaccines against pathogens, new information on the minor histocompatibility complex, and much more. Moreover, the author brings you up to date with the latest developments by reviewing recently proposed concepts on transplantation immunology, blocking of costimulatory signals, CTLA-4 mediated T-cell inhibition, immune tolerance, NK cell tolerance, HLA delivered peptides for immunosuppression, and tumor antigens coded by oncogens.

Covering subject matter based on the immunology course taught by the author for the past twenty years, Introduction to Immunology is an excellent text for graduate and postgraduate students, as well as a good reference book for teachers of biological sciences.

Contents

1. Introduction
2. Innate Immunity
3. Acquired Immunity (Adaptive Immunity)
4. Cells and Organs of Immune System
5. Antigens or Immunogens
6. Major and Minor Histocompatibility Complex
7. Antibodies (Immunoglobulins(
8. Antigen Antibody Interactions
9. Immunoglobulin Genes-Organization and Expression
10. B-Cell Maturation, Activation, and Differentiation
11. T-Cell Maturation, Activation, and Differentiation
12. T-Cell and B-Cell Receptors
13. Antigen Processing and Presentation
14. Effector Responses of Cell-Mediated and Humoral Immunity
15. Cytokines
16. Complement System
17. Vaccines
18. Immune Response to Infectious Diseases
19. Hypersensitivity
20. Transplantation Immunology
21. Immunologic Tolerance
22. Immunology of Tumors
23. Autoimmune Diseases
24. Immunodeficiency Diseases

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