Liposome Technology
Volume One
Liposome Preparation and Related Techniques
edited by
Gregory Gregoriadis

Ordering Information

Contents

1. Formation and Properties of Fatty Acid Vesicles (Liposomes)
2. Formation and Physicochemical Properties of Lipid Vesicles (Liposomes) by the Coacervation Method
3. Preparation of Liposomes and Oily Formulations by Freeze-Drying Monophase Solutions
4. Formation of Large Unilamellar Vesicles by Extrusion
5. Preparation of Liposomes for Pulmonary Delivery Using Medical Nebulizers
6. Immunopotentiating Reconstituted Influenza Virosomes
7. Lipoplexes in Gene Therapy under the Considerations of Scaling Up, Stability Issues and Pharmaceutical Requirements
8. Synthesis and Advantages of Acid-Labile Formulations for Lipoplexes
9. Bioresponsive Lipids and Their Use for Macromolecular Delivery
10. Polymeric Vesicles Based on Hydrophilic Polymers Bearing Hydrophobic Pendant Groups
11. Mixed Vesicles and Mixed Micelles: Formation, Thermodynamic Stability and Pharmaceutical Aspects
12. Vesicular Phospholipid Gels
13. Stabilization of Liposomes by Freeze-Drying: Lessons from Nature
14. Hydrolysis of Phospholipids in Liposomes and Stability Indicating Analytical Techniques
15. Process Development and Quality Control of Injectable Liposomal Therapeutics

Index

Liposome Technology
Volume Two
Entrapment of Drugs and Other Materials into Liposomes
edited by
Gregory Gregoriadis

Ordering Information

Contents

1. Amphipathic Weak Base Loading into Preformed Liposomes Having a Transmembrane Ammonium Ion Gradient: From the Bench to Approved DOXIL
2. Encapsulation of Drugs within Liposomes by pH Gradient Techniques
3. Incorporation of Lipophilic Antitumor and Antiviral Drugs into the Lipid Bilayer of Small Unilamellar Liposomes
4. Liposome-Encapsulated Hemoglobin as an Artificial Oxygen Carrier
5. An Original Lipid Complex System for Amphotericin B
6. Coupling of Peptides to the Surface of Liposomes: Application to Liposome-Based Synthetic Vaccines
7. Encapsulation of Nucleic Acid-Based Therapeutics
8. Intraliposomal Trapping Agents for Improving In Vivo Liposomal Drug Formulation Stability
9. Radiolabeling of Liposomes for Scintigraphic Imaging
10. Liposomal Bisphophonates for the Treatment of Restenosis
11. Development of a Liposomal Vaccination System for Immunity Modulating Anti-Tumor Therapy
12. Influenza Virosomes as Adjuvants in Cancer Immunotherapy
13. Liposome-Based DNA/Protein Vaccines: Procedures for Entrapment
14. LPD: A Non-Viral Gene Vector Turned into a Potent Vaccine Carrier
15. Automated Screening of Cationic Lipid Formulations for Transfection
16. Association of Neutral or Anionic PEG Lipids into Lipoplexes: On Line Incorporation Assessment, and Pharmacokinetics Advantages
17. Lipid Peptide Vectors for Gene Therapy
18. Phospholipid and Non-Phospholipid Based Vesicles for Drug and DNA Delivery to Mitochondria in Living Mammalian Cells
19. Uptake and Intracellular Fate of Liposomes

Index

Liposome Technology
Volume Three
Interactions of Liposomes with the Biological Milieu
edited by
Gregory Gregoriadis

Ordering Information

Contents

1. Interactions of Liposomes with Complement Leading to Toxic Reactions
2. Fixed Drug Ratio Liposome Formulations of Combination Cancer Therapeutics
3. Pharmacokinetics and Biopharmaceutics of Lipid-Based Drug Formulations
4. Optimization Strategies in Lymph Node Targeting of Interstitially Injected Immunoglobulin G-bearing Liposomes
5. Observations on the Disappearance of the Stealth Property of PEGylated Liposomes: Effect of Lipid Dose and Dosing Frequency
6. ATP-Loaded Liposomes for Myocardium Preservation under Ischemic Conditions
7. Targeting Tumor Angiogenesis Using Liposomes
8. Targeting Liposomes to Endothelial Cells in Inflammatory Diseases
9. Targeting of Cationic Liposomes to Endothelial Tissue
10. Folate Receptor Targeted Liposomes. Methods for Tracking Radiolabeled Liposomes after Injection in the Body
11. Cytoplasmic Tracking of Liposomes Containing Protein Antigens
12. Targeting of Liposomes to Lymph Nodes. Intracellular Delivery of Therapeutic Oligonucleotides in pH-Sensitive and Cationic Liposomes
13. Liposomes for Intracavitary and Intratumoral Drug Delivery
14. The Liposome Mediated "Macrophage Suicide" Technique: A Tool to Study and Manipulate Macrophage Activities
15. Lung Surfactants: Correlation Between Biophysical Characteristics, Composition and Therapeutic Efficacy
16. Liposomes in Cancer Immunotherapy
17. Preparation of Oil-in-Water Emulsions Stabilized by Liposomes for Vaccine Delivery
18. A Biotechnological Approach to Formulate Vaccines within Liposomes
19. Liposomal Therapeutics: From Animal to Man

Index

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