Liver Diseases presents state-of-the-art information summarizing the current understanding of a range of liver diseases, and reviews some key diagnostic and therapeutic advances.

Features:

• Treats the cellular, biochemical and immunological mechanisms underlying liver diseases
• Focuses on clinical liver disease pathophysiology and related diagnostics and therapeutic insights
• Targets hepatologists, clinicians, researchers and cademicians

Contents

Volume 1: Liver Diseases: Pathways, Mediators and Regulation

Liver Diseases: Mediators and Regulation

• Ubiquitin - Proteasome Pathway in the Pathogenesis of Liver Disease
• Bardag-Gorce
• Collagen Gene Regulation in the Hepatic Stellate Cell
• CYP2F1-Biochemical and Toxicological Aspects and Role in Alcohol-induced Liver Injury
• Alcohol and Methyl Transfer: Implications for Alcohol-Related Hepatocarcinogenesis
• Menthionine Adenosyltransferase and S-adenosylmethionine in Liver Health and Disease
• Acetone Metabolism in the Liver
• Oxidative Stress and Liver Fibrosis: From Liver Injury to Modulation of Cell Signalling and Response
• Role of Nitric Oxide in Liver Disorders
• Renin-Angiotensin System in Liver Fibrosis

Immunological Basis of Liver Injury

• Cell and Molecular Mechanisms in the Development of Chronic Liver Inflammation
• Role of Activated Macrophages in Liver Disease
• Investigations into Basis for Immune Recognition of Cellular Targets in Primary Biliary Cirrhosis
• Cross Talk of Hepatocytes and Nonparenchymal Liver Cells in Physiology and Pathology
• Monoxides and Eicosanoids
• Activity of Cytokines in Chronic HCV Infection and
• Influence of Antiviral Drugs
• Role of Chemokines in Liver Pathophysiology

Volume 2: Clinical Liver Diseases: Pathophysiology, Diagnostic and Therapeutic Insights

Clinical Liver Disease Pathophysiology

• Nonalcoholic Fatty Liver Diseases
• Clinical and Pathophysiological Features
• Genetic Basis of Hepatocellular Cancer
• Haemochromatosis
• Recent Advances
• Pathophysiology of Cirrhotic Ascites
• Cryptogenic Hepatitis
• HIV-1 and the Liver
• Cell Death by Necrosis
• Mechanisms and Interception in the Liver
• Fulminant Hepatic Failure: Etiology, Pathogenesis, and Treatment

Therapeutic and Diagnostic Insights

• Advances in Biology and Therapy of Hepatitis B Virus Infection
• Hepatitis C Virus
• Molecular Virology and Therapeutic Targets
• Drug Targeting to Hepatic Stellate Cells
• A New Strategy to Treat Liver Fibrosis
• Developing Therapeutic Strategies for Hepatic Fibrosis
• Liver Disease, Oxidative Stress and Ursodeoxycholic Acid
• Plasma TGF-b as a Diagnostic and Prognostic Marker
• Hepatocytes as the Gold Standard for Predicting in-vivo Hepatotoxicity of Xenobiotics Using Accelerated Cytotoxicity Mechanism Screening Techniques

Index

click here to see books • videos • cd-roms of related interest