A Biosynthetic Approach
Second Edition
by Paul M. Dewick
Medicinal Natural Products provides a comprehensive and balanced introduction to natural products from a biosynthetic perspective. The book builds upon fundamental chemical principles and guides the reader through a wealth of diverse natural metabolites with particular emphasis on those used in medicine:
- Sources
- Production methods
- Use as drugs
- Semi-synthetic derivatives
- Synthetic analogues
- Modes of action
The Second Edition retains the user-friendly style and highly acclaimed features of the First Edition, and has been extended and fully updated:
- A comprehensive treatment of plant, microbial and animal products natural products in one volume including the latest developments in the field
- Expanded coverage of many topics
- New material including genetic manipulation of biosynthetic pathways and the mevalonate-independent pathway to terpenoids
- Extensive use of chemical schemes with annotated mechanistic explanations
- Cross-referencing to emphasize links and similarities
Contents
- About this book and how to use it
- Secondary metabolism: The building blocks and construction mechanisms
- The acetate pathway: Fatty acids and polyketides:
- The shikimate pathway: Aromatic amino acids and phenylpropanoids
- The Mevalonate and Deoxyxylulose Phosphate Pathways : Terpenoids and Steroids
- Alkaloids
- Peptides, proteins and other amino acid derivatives
- Carbohydrates
Index
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