Management Strategies in Antithrombotic Therapy offers a comprehensive review of antithrombotic therapy, including the latest therapies, risk factors and evidence-based strategy.

Management Strategies in Antithrombotic Therapy acquaints readers with the data behind the commonly used antithrombotic agents and assists them in formulating a sound, evidence-based therapeutic strategy appropriate for each patient.

Contents

Thrombosis and Antithrombotics in Vascular Disease

1. The Burden of Thrombosis
2. Essential components of thrombosis
3. Thrombosis in the acute ischemic syndromes
4. Venous thromboembolic disease
5. The ideal antithrombotic agent

Aspirin

1. Pharmacology
2. Clinical uses of aspirin

Thienopyridines – Ticlopidine and Clopidogrel

1. Pharmacology
2. Clinical uses of the thienopyridines

Platelet Glycoprotein IIb/IIIa Inhibitors

1. GP IIb/IIIa receptor inhibitors
2. GP IIb/IIIa inhibitors during percutaneous coronary revascularization
3. GP IIb/IIIa inhibitors in the management of non-st-elevation ACS
4. GP IIb/IIIa inhibitors in the management of acute STEMI
5. Safety of GP IIb/IIIa inhibitors

Unfractionated Heparin

1. Pharmacology
2. Clinical uses of UH
3. Clinical considerations

Low-Molecular-Weight Heparins

1. Comparisons between UH and LMWH
2. Clinical uses of LMWH

Direct Thrombin Inhibitors

1. Overview of DTIs
2. Clinical uses of DTIs

Fibrinolytic agents

1. Fibrinolytic agents for STEMI
2. Fibrinolytics for VTE

Acute ST-Segment-Elevation Myocardial Infarction

1. Definitive therapy
2. Adjunctive therapy

Acute Coronary Syndromes: Unstable Angina /Non-ST-Segment-Elevation Myocardial Infarction (NSTE ACS)

1. Antithrombotic approach to patients with ACS/NSTEMI
2. Early invasive versus early conservative strategies

Anticoagulation Strategies for Patients Undergoing Percutaneous Coronary Intervention

1. Antiplatelet therapy
2. Antithrombotic therapy
3. Special populations

Venous Thromboembolic Disease

1. Risk of VTE.
2. Prevention of VTE
3. Treatment of VTE

Heparin-Induced Thrombocytopenia

1. Incidence
2. Pathogenesis
3. Clinical manifestations
4. Diagnosis
5. Prevention
6. Treatment

Index

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