Microbial Foodborne Diseases: Mechanisms of Pathogenesis and Toxin Synthesis

Microbiology Reference from C.H.I.P.S.

Microbial Foodborne Diseases:
Mechanisms of Pathogenesis and Toxin Synthesis

edited by Jeffrey W. Cary, John E. Linz, and Deepak Bhatnager

Microbial Foodborne Diseases: Mechanisms of Pathogenicity and Toxin Synthesis covers selected organisms from five major pathogen groups including Gram positive and Gram negative bacteria, toxigenic fungi and marine organisms, parasitic protozoa, and viruses and related infectious agents.

Recognized authorities in the field provided each chapter. These chapters contain detailed, up-to-date information on the molecular mechanisms of pathogenesis, including virulence factors and toxins which influence adherence, colonization, host-cell entry, and resistance to host immune response mechanisms. Chapters on toxigenic fungi and marine dinoflagellates cover advances in the molecular biology of toxin synthesis in detail. Microbial Foodborne Diseases also discusses important new areas of research, with implications toward the development of strategies for the control of the disease process.

Focuses on molecular biology of pathogenicity and toxin production in the foodborne and waterborne pathogens critical to food safety.
Detailed coverage of the most important bacterial, fungal, protozoan and viral pathogens—and their impact on human health and economic concerns
Detailed chapters on prion-based BSE ("Mad Cow" disease) and Norwalk virus associated diseases
Most comprehensive review to date on molecular biology of aflatoxins
Includes detailed discussions of Fusarium toxins and PSP toxins of marine dinoflagellates

Contents

Part I: Gram Negative Foodborne Bacterial Pathogens

Molecular and Cellular Biology of Salmonella Pathogenesis Francisco Garcia del Portillo
Shigella Infections: Epidemiology, Pathogenesis and Host Immune Response Christine Wennerås and Philippe J. Sansonetti
The Molecular Pathogenesis of Escherichia coli Infections Michael S. Donnenberg and James P. Nataro
Virulence Determinants of Yersinia enterocolitica: Mode of Action and Global Regulation Marie-Paule Sory and Guy R. Cornelis
Molecular Pathogenesis of Vibrio Infections Kenneth M. Peterson
Molecular Mechanisms Governing Campylobacter Pathogenicity Linda S. Mansfield and Sheila R. Abner

Part II: Gram Positive Foodborne Bacterial Pathogens

The Genetics, Synthesis, and Action of Clostridium perfringens Enterotoxin Bruce A. McClane
Mechanisms of Pathogenesis and Toxin Synthesis in Clostridium botulinum Keiji Oguma, Yukako Fujinaga, Kaoru Inoue, and Kenji Yokota
Pathogenesis Determinants of Listeria monocytogenes Sophia Kathariou Fungal and Marine Toxins
Aflatoxins: Biological Significance and Regulation of Biosynthesis Jeffrey W. Cary, Deepak Bhatnagar, and John E. Linz
Fusarium Toxins: Molecular Biology of Trichothecene and Fumonisin Biosynthesis Robert H. Proctor
PSP toxins: Their Biosynthesis by Marine Dinoflagellates and Molecular Identification Yuzaburo Ishida and Yoshihiko Sako

Part III: Parasitic Protozoa

Toxoplasma Gondii Strain Variation and Pathogenicity Judith E. Smith and Naomi Rebuck
Virulence Associated Factors of Enteric Protozoans Entamoeba histolytica & Cryptosporidium parvum Upinder Singh, Theodore S. Steiner, and Barbara J. Mann

Part IV: Viruses and Related Infectious Agents

Norwalk and Other Human Caliciviruses: Molecular Characterization, Epidemiology, and Pathogenesis Kellogg J. Schwab, Mary K. Estes, and Robert L. Atmar
Molecular Biology of Prion Disease Corinne Ida Lasmézas and Stefan Weiss

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Microbial Foodborne Diseases:
Mechanisms of Pathogenesis and Toxin Synthesis
edited by Jeffrey W. Cary, John E. Linz, and Deepak Bhatnager
550 pages • $218.95 + shipping

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