Nanomaterials for Medical Diagnosis and Therapy goes on to look at nanoparticle-based magnetic resonance, molecular and other imaging applications, as well as the potential roles of carbon nanotubes and bionanoparticles in biomedical applications.

Nanomaterials for Medical Diagnosis and Therapy focuses on:

• drug delivery systems based on nonporous and nanosize materials
• solid lipid and polymeric nanoparticles
• intelligent hydrogels
• core-shell nanoparticles
• nanocapsules

Contents

1. Nanotechnologies for Diagnosis – Present and Future

• Nanotechnology and Patient Diagnostics
• Optical
• Electrical
• Magnetic
• Mechanical
• Imaging Diagnostics
• Nanotechnology-enhanced Tools
• Nanotechnology and the Future of Patient Diagnostics

2. Superparamagnetic Nanoparticles of Iron Oxides for Magnetic Resonance Imaging Applications

• Physicochemical Characteristics
• Pharmacology and Metabolism
• Current Clinical Uses and Future Developments
• Conclusion

3. Carbon Nanotube-based Vectors for Delivering Immunotherapeutics and Drugs

• Chemical Functionalization of CNTs
• CNTs in Diagnosis
• CNT Cell Uptake
• CNTs as Delivery Devices for Antigens and Adjuvants
• CNTs for Drug Delivery
• CNTs for Gene Transfer
• Health Impact of CNTs
• General Conclusions

4. Core–Shell Nanoparticles for Drug Delivery and Molecular Imaging

• Core–shell Nanoparticles with a Lipid Core
• Core–Shell Nanoparticles with a Polymeric Core
• Core–shell Nanoparticles with a Metallic Core
• Conclusions

5. Nanotechnologies for Targeted Delivery of Drugs

• Basic and Special Pharmacology
• Strategies for Targeted Delivery – Observed in Nature
• Strategies for Targeted Delivery – Designed by Man
• Conclusion and Outlook

6. Nanoporous and Nanosize Materials for Drug Delivery Systems

• Nanomaterials for Coating
• Materials for Nanoparticulate Therapy and Diagnosis
• Nanoporous Materials as Drug Delivery System Carriers
• Physicochemical Aspects of Porous Silastic Materials for Drug Delivery

7. NANOEGG1 Technology for Drug Delivery

• New Nanoparticles with a Core–Shell Structure: The NANOEGG System
• NANOEGG for Dermatological Aspects
• Why does NANOEGG Show the High Performance on the Improvement of Brown Spot and Wrinkles
• NANOEGG for Other Indications
• NANOEGG for Other Drugs
• Conclusion

8. Polymeric Nanomaterials – Synthesis, Functionalization and Applications in Diagnosis and Therapy

• Polymer Materials Used for the Synthesis of Nanoparticles
• Preparation of Polymeric Nanoparticles
• Surface Functionalization
• Applications
• Conclusion and Perspectives

9. Polymeric Nanoparticles for Drug Delivery

• Application of Nanoparticles for Noncancer Applications
• Drug Delivery
• Conclusions

10. Solid Lipid and Polymeric Nanoparticles for Drug Delivery

• SLNs
• Polymeric Nanoparticles

11. Intelligent Hydrogels in Nanoscale Sensing and Drug Delivery Applications

• Intelligent Hydrogels
• Sensor Applications
• Drug Delivery Applications
• Conclusions

12. Nanoshells for Drug Delivery

• Metallic Nanoshells
• Nanoshells Formed by Polyion E-LbL Self-assembly
• Conclusion

13. Bionanoparticles and their Biomedical Applications

• BNPs
• Genetic and Chemical Alterations of BNPs
• BNPs in Therapeutics
• Immune Response
• Future Directions

14. Nanotechnology for Gene Therapy – HVJ-E Vector

• Biological Barriers to Gene Transfer
• HVJ-E Vector
• Biocompatible Polymer with HVJ-E
• Magnetic Nanoparticles for Medicine
• Conclusion

15. Nanotoxicology of Synthetic Gene Transfer Vectors: Poly(ethyleneimine)- and Polyfectin-mediated Membrane Damage and Apoptosis in Human Cell Lines

• PEI as a Nonviral Vector
• PEI-mediated Cell Dysfunction and Apoptosis
• Cell Damage and Apoptosis with Related Polycations and Cationic Lipids
• Conclusions and Future Outlook

16. Nanoparticles for the Treatment of Alzheimer’s Disease: Theoretical Rationale, Present Status and Future Perspectives

• Rationales: The Ability of Nanoparticles to Cross the BBB – A Useful Tool to Deliver Drugs into the Brain
• Status: Nanoparticle Targeting Transport of Therapeutic Agents for Potential Treatment of AD
• Perspective

Index

click here to see books • videos • cd-roms of related interest