by Anthony J. Hickey
and David Ganderton

Summarizing fundamental engineering principles and operations critical to converting bulk pharmaceutical products into patient-ready and appropriate drug delivery dosage forms, Pharmaceutical Process Engineering facilitates a comprehensive understanding of the practical aspects of drug production in an accessible, step-by-step format.

Features:

• the application of key concepts and major unit operations in pharmaceutical engineering
• principles of heat transfer, mass transfer, and fluid flow
• control of global and local manufacturing environments
• the preparation of sterile materials such as water for injection
• drying, evaporation, and crystallization processes for concentrated drug solutions and solids
• techniques of filtration and centrifugation for collecting or removing drug particles
• particle size reduction, mixing, granulation, and drying methods for capsule and tablet
• the manufacture of biological materials
• and more!

Pharmaceutical Process Engineering makes a noteworthy reference for industrial, research, and clinical pharmaceutical scientists; chemical and industrial engineers; biologists and toxicologists; biostatisticians; analytical chemists; and quality control, quality assurance, and regulatory compliance managers; and serves as an essential text for upper-level undergraduate and graduate students in these disciplines.

Contents

1. Fundamentals
   • Fluid Flow
   • Heat Transfer
   • Mass Transfer
   • Powders

2. Processes
   • Air Conditioning and Humidification
   • Drying
   • Solid-Liquid Extraction
   • Crystallization
   • Evaporation and Distillation
   • Filtration
   • Size Reduction and Classification
   • Mixing
   • Solid Dosage Forms
   • Sterilization
   • Bioprocessing

Index

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