Mechanisms of Action
by Mark S. Meskin et al
Features
- Presents quality research data from leading researchers
- Focuses on issues not covered or not covered well in other references
- Includes discussion of gene regulation and gene expression
Phytochemicals: Mechanisms of Action is the fourth volume of a series presenting cutting-edge, scientific research-based discussions of the roles of phytochemicals in disease prevention and health promotion. It presents the latest research data on chemicals not covered in previous volumes in the series and focuses on three areas:
- pharmacokinetics and bioavailability (Do phytochemicals get into the body? How are they metabolized?)
- mechanisms of actions (How do phytochemicals work at the cellular level?)
- clinical outcomes and methodology (What data are available to demonstrate their clinical efficacy? What are reasonable biomarkers?)
Contents
- Absorption and metabolism of anthocyanins and other phenolics in human subjects
- Absorption and metabolism of the dietary phytochemical, quercetin
- Biotransformation and bioavailability of tea polyphenols
- The importance of in vivo metabolism of polyphenols and their biological action
- Cancer prevention by phytochemicals, modulation of cell cycle
- Cancer chemoprevention by phytochemicals including flavanoids and flavanoids through modulating signal transduction pathways
- Gene regulatin by glucosinolate hydrolysis products
- Healthy foods versus phytosterol fortified foods for the primary prevention of coronary artery disease
- Vascular effects of resveratrol
- Development of a mixture of dietary carotenoids as cancer chemopreventive agents: C57BL/6J mice as a useful animal model for efficacy studies with carotenoids
- Chemoprevention of colon cancer by curcumin
- High-precision gene expression analysis of complex therapeutic agents: a comparison of the anti-inflammatory and immuno-regulatory effects of certain herbals and pharmaceuticals
Index
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