Product Safety Evaluation Handbook
Second Edition
edited by Shayna Cox Gad
This completely revised and expanded reference
provides comprehensive, single-source coverage of the latest toxicity testing
requirements and methods for personal care products, industrial and agricultural
chemicals, and consumer goods.
Focusing on product safety techniques and regulatory requirements developed
and instituted since the original edition was published a decade ago, the
Second Edition of the Product Safety Evaluation Handbook
- contains a new chapter on toxicokinetic testing and modeling
- offers the latest solutions to common problems in testing and risk assessment
- supplies an updated bibliography and more than 1300 references—over 100 new to this edition—to facilitate further study
- presents recent data relevant and valid for the global market
- clarifies and evaluates novel program design hazards
- advises on the precise design, execution, and analysis of studies
- gives a new emphasis to an understanding of the physical properties of products
- furnishes up-to-the-minute information on collecting, tabulating, and comparing data
- establishes improved criteria for assessing laboratory competency
- and more!
The Product Safety Evaluation Handbook, Second Edition serves as a companion
in the interactive, multidisciplinary process of defining and developing
a data package for product safety evaluation programs, and meets the needs
of toxicologists, pharmacologists, clinical and histopathologists, biochemists,
industrial hygenists, product safety and laboratory managers, and advanced
undergraduate and graduate students in these disciplines.
Contents
- Defining the Objective: Product Safety Assessment Program Design and Scheduling
- Toxicology Information Sources and Their Use
- Acute Systemic Toxicity Testing
- Evaluating Products for Their Potential to Cause Dermal and Ocular
Irritation and Corrosion
- Predicting Dermal Hypersensitivity Responses
- Genetic Toxicology Testing
- Repeated-Dose Toxicity Studies
- Neuro- and Behavioral Toxicology Testing
- Techniques for Evaluating Hazards of Inhaled Products
- Reproductive Hazards
- Developmental Toxicology
- Assessment and Modeling of the Biological Hazards of Combustion Products
- Practical Statistical Analysis
- Placing and Monitoring Testing at External Facilities
- Hazard and Risk Assessment
- Toxicokinetic Studies in the Commercial Development of Agricultural
and Industrial Chemical Products
Index