This timely resource analyzes the function of specific enzymes in the complex processes of protein conformation, assembly, and stability - comprehensively addressing the folding of proteins to natural states as well as cotranslational and postranslational modifications that effect function.

Contents

Prolyl 4-Hydroxylase: An Overview.
Prolyl 4-Hydroxylase Inhibitors.
Occurrence of Dihydroxyproline in Proteins and Peptides.
Distribution and Expression of Prolyl 4-Hydroxylase-b Subunit/Protein Disulfide Isomerase in Vertebrate Cells.
Prolyl 4-Hydroxylase and Protein Disulfide Isomerase in Plants.
Protein Disulfide Isomerase from Soybean: Isolation, Structure, and Function in Protein Folding.
Physiological Roles of the Thiol: Protein Disulfide Oxidoreductases.
HIP-70/GRP58/ERp61/PLC-a/CPT: A Single Gene Product and Member of the Protein.
Disulfide Isomerase Gene Family with Thiol Oxidoreductase Activity Subject to Neuroendocrine Regulation.
Estrogen-Responsive Domain of Protein Disulfide Isomerase.
Protein Disulfide Isomerase as a Novel Target for ATP.
The Thioredoxin System and Thioredoxin Domains of Protein Disulfide Isomerase from the Endoplasmic Reticulum.
Chaperone Activity of Protein Disulfide Isomerase.
Protein Disulfide Isomerase and the Complications of Protein Folding.
The Peptide Binding Site of Protein Disulfide Isomerase.
Protein Disulfide Isomerase as a Component of Muscle Sarcoplasmic Reticulum.
Microsomal Triglyceride Transfer Protein: A Heterodimer Consisting of Protein Disulfide Isomerase and a Unique Large Subunit.
Reductive Function of PDI at the Surface of Mammalian Cells: Its Role in Diphtheria Toxin Translocation and HIV Entry into Human Cells.
Structural Analysis of the b Subunit of Prolyl 4-Hydroxylase.
Retina Cognin: A Tissue-Specific PDI-Related Protein Involved in Cell Signaling.
Protein Disulfide Isomerase: A Putative Calcium Storage Protein in the Endoplasmic Reticulum.
Protein Disulfide Isomerase: Cellular Enzymology of the CXXC Motif.
Protein Disulfide Isomerase: Use in the Production of Recombinant Pharmaceutical Proteins.

click here to see books • videos • cd-roms of related interest