Skin Delivery Systems
Transdermals, Dermatologicals, and Cosmetic Actives
edited by John J. Wille

Skin Delivery Systems: Transdermals, Dermatologicals and Cosmetic Actives brings together the emerging fields of cosmetic actives with new advances in skin delivery technologies. It provides a methodical and systematic explanation of technologies used to transport pharmaceuticals and cosmetic actives through the skin's barriers.

Features:

• basic principles of dermatology and skin penetration
• describes and explains the most current methods of transdermal transport
• new materials, such as amphiphilic polymers
• new formulation methods, such as miniemulsions
• variations on technologies such as sonophoresis and iontophoresis

Skin Delivery Systems: Transdermals, Dermatologicals and Cosmetic Actives also shows the connections between skin penetration and a variety of active substances, including specialized pharmaceuticals and natural and botanical ingredients used in cosmetics. It also presents critical empirical data and design information intended to assist researchers, product developers, and testers in the pharmaceutical and cosmetics industries.

Contents

Section I: General Skin Considerations

1. Fundamental Concepts in Skin Reactivity
2. Skin Barrier Strategies
3. Abrogation of Skin Reactions: Methods and Agents
4. Clinical Perspectives on the Efficacy of Cosmetic Actives (Cosmeceuticals)

Section II: Novel Topical Actives

5. Phytocosmeceuticals
6. Hydroxy Acid Delivery Systems Application for Treatment of Acne
7. Role of Energy Metabolites in Skin Aging and Protection

Section III: Trends in Skin Therapy

8. Current Trends in Dermatologicals
9. Topical Treatment of Skin Diseases
10. Corneotherapy: Novel Topical Treatments of the Stratum Corneum

Section IV: Novel Skin Delivery Systems

11. Skin Care Delivery Systems: Overview
12. Emulsions: Factors and Issues in Formulation
13. PharmaDur™: Bioadhesive Delivery System
14. Thixogel: A Starch Matrix Encapsulation Technology and Topical and Cosmetic Delivery
15. Nanogels in Cosmetics and Personal Care Products

Section V. Transdermal Drug Delivery Technologies

16. Transdermal Drug Delivery Developments: Patent Review
17. Chemical Enhancers
18. Accelerated Development of Topical and Transdermal Delivery Systems
19. Microneedles for Drug and Vaccine Delivery
20. Pulsatile “Smart” Drug Delivery
21. Microfluidics for Transdermal Drug Delivery
22. Future Considerations for Advanced Delivery Systems

Index

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