St. John's Wort and its Active Principles in Depression and Anxiety reviews the available data related to the biochemical, functional, and behavioural pharmacology of Hypericum and its active constituents.

St. John's Wort and its Active Principles in Depression and Anxiety reviews the available data related to the biochemical, functional, and behavioural pharmacology of Hypericum and its active constituents.

Contents

1. Introduction and Historical Outline
2. Phytochemistry
3. St. John's Wort and its Active Principles in Depression and Anxiety- A Critical Analysis of Receptor Binding Studies
4. Effects on Transmitter Uptake and Their Cellular and Molecular Basis
5. Modulation of Neurotransmitter Release and Metabolism
6. Efficacy in Behavioural Models of Antidepressant Activity
7. Comparative Preclinical Antidepressant Activity
8. Hyperforin and Efficacy in Animal Models for Anxiety and Cognition
9. Pharmacokinetics and Biopharmaceuticals
10. Clinical Efficacy in Depression
11. Clinical Efficacy of St. John's Wort in Psychiatric Disorders Other than Depression

Index

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