edited by Kuo-Hsiung Lee
and Hidoji Itokawa

In this volume, the authors provide an authoritative account of the taxoids. It covers their production and biosynthesis—from commercial cultivation to plant tissue culture methods—describes taxoid chemistry, the analytical methods for identifying their structure and the pharmacological and pre-clinical aspects important in investigating their therapeutic actions.

Taxus: The Genus Taxus presents a thorough review of the scientific literature, including data from scientists currently engaged in taxoid research, and will be of significant value to researchers and others who wish to gain a practical perspective on taxoid research and development.

Contents

1. Introduction
2. Biosynthesis of Taxoids
3. Taxoids Occurring in the genus Taxus
4. Physical Methods for Identifying the Structures of Taxoids
5. Plant Tissue Culture of Taxoids
6. The Commercial Cultivation of Taxus Species and Production of Taxoids
7. Analytical Aspects of Taxoids
8. Chemistry of Taxol and Related Taxoids
9. Total Synthesis of Taxoids
10. Structure-Activity Relationships of Taxoids
11. Pre-clinical and Clinical Investigation of the Taxanes
12. Paclitaxel Content of Yews in Ireland

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