Third Edition
edited by Ernest Hodgson

A state-of-the-art toxicology textbook—ideal for students and professionals!

Now in its Third Edition, this unique resource that provides both students and practitioners with a wide-ranging, accessible overview of the discipline. Suitable for courses in environmental, pharmacological, medical, and veterinary toxicology, this essential text features chapters written by experts who address a range of key topics.

A Textbook of Modern Toxicology is distinguished by up-to-date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity testing, ecological risk assessment, and many other areas of toxicology that help foster a solid comprehension of the field.

The new edition reflects the addition of new contributors who offer the latest thinking in their respective areas of specialization and in their examination of emerging topics such as molecular biological aspects of technology.

A Textbook of Modern Toxicology emphasizes the biochemical aspects of toxicology, underscoring the belief that progress in toxicology hinges on an understanding of the fundamentals of toxic action at the cellular and molecular levels. To reinforce the text material, the book features chapter-ending suggestions for further reading, a helpful glossary, and a special summary section.

Contents

1. Introduction
   1. Introduction to Toxicology
   2. Introduction to Biochemical and Molecular Methods in Toxicology
   3. Toxicant Analysis and Quality Assurance Principles

2. Classes of Toxicants
   4. Exposure Classes, Toxicants in Air, Water, Soil, Domestic and Occupational Settings
   5. Classes of Toxicants: Use Classes

3. Toxicant Processing In Vivo
   6. Absorption and Distribution of Toxicants
   7. Metabolism of Toxicants
   8. Reactive Metabolites
   9. Chemical and Physiological Influences on Xenobiotic Metabolism.
   10. Elimination of Toxicants

4. Toxic Action
   11. Acute Toxicity
   12. Chemical Carcinogenesis
   13. Teratogenesis

5. Organ Toxicity
   14. Hepatotoxicity
   15. Nephrotoxicity
   16. Toxicology of the Nervous System
   17. Endocrine System
   18. Respiratory Toxicity
   19. Immunotoxicity
   20. Reproductive System

6. Applied Toxicology
   21. Toxicity Testing
   22. Forensic and Clinical Toxicology
   23. Prevention of Toxicity
   24. Human Health Risk Assessment

7. Environmental Toxicology
   25. Analytical Methods in Toxicology
   26. Basics of Environmental Toxicology
   27. Transport and Fate of Toxicants in the Environment
   28. Ecological Risk Assessment

8. Summary
   29. Future Considerations for Environmental and Human Health

Glossary
Index

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