by Merlin Willcox et al

• Explores the evidence for the safety and efficacy of traditional herbal medicines to treat malaria

• Presents systematic reviews of the literature and consensus guidelines

• Includes detailed case studies

Traditional Medicinal Plants and Malaria explores the evidence for the safety and efficacy of some of these traditional medicines, and presents practical guidelines for designing studies on traditional plant-based antimalarial medicines, mosquito repellents, and insecticides.

Systematic reviews of the literature and consensus guidelines form the main body of the book. Ethnomedical, ethnobotanical, pharmacological, phytochemical, toxicological, and clinical aspects of herbal antimalarials are also reviewed. These are supplemented by case studies of the most well-known traditional antimalarials.

Contents

1. TRADITIONAL MEDICINE AND MALARIA CONTROL
   • Malaria Control in Africa and the Role of Traditional Medicine

2. CASE STUDIES OF PLANT-BASED MEDICINES FOR MALARIA
   • Cinchona
   • Artemisia annua
   • Ferreira
   • Changshan (Diechroa febrifuga)
   • "Ayush-64"
   • Neem (Azadirachta indica)
   • "Malarial"
   • Cryptolepis sanguinolenta
   • Strychnos myrtoides

3. ETHNOMEDICAL RESEARCH
   • Frequency of Use of Traditional Herbal Medicines for the Treatment and Prevention of Malaria: An
   • Overview of the Literature
   • An Overview of Ethnobotanical Studies on Plants Used for the Treatment of Malaria
   • The Discovery of Indigenous Febrifuges in the British East Indies, c. 1700-1820
   • The Ayurvedic Perspective on Malaria
   • Guidelines for Ethnobotanical Studies on Traditional Antimalarials

4. LABORATORY RESEARCH
   • An Overview of the Pharmacological Properties of Traditional Herbal Antimalarials
   • Guidelines for the Non-clinical Evaluation of the Efficacy of Traditional Antimalarials
   • Models for Studying the Effects of Herbal Antimalarials on Non-Erythrocytic Stages of Malaria
   • Guidelines for the Preclinical Evaluation of the Safety of Traditional Antimalarials

5. CLINICAL RESEARCH
   • An Overview of Clinical Studies on Traditional Herbal Antimalarials
   • Observational Methods for Assessing Traditional Antimalarials
   • Guidelines for Clinical Studies on Herbal Antimalarials

6. REPELLENCE AND VECTOR CONTROL
   • An Overview of Plants Used as Insect Repellents
   • Guidelines for Studies on Plant-based Insect Repellents
   • An Overview of Plants Used for Vector Control
   • Guidelines for Studies on Plant-based Vector Control Agents

7. EPILOGUE: PROSPECTS FOR THE FUTURE

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