Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes.

Key Features of the Sixth Edition:

• Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases
• MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners
• More than 1,200 high-quality, full-color illustrations
• A concise appendix reviewing important Organic Chemistry Concepts

New to the Sixth Edition:

• Fully Updated with a significant revision of all chapters and major topics
• Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer
• A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors

Contents

Structure of Macromolecules

1. Eukaryotic Cell Structure
2. DNA and RNA: Composition and Structure
3. Proteins I: Composition and Structure

Transmission of Information

4. DNA Replication, Recombination, and Repair
5. RNA: Transcription and RNA Processing
6. Protein Synthesis: Translation and Posttranslational Modifications
7. Recombinant DNA and Biotechnology
8. Regulation of Gene Expression
9. Proteins II: Structure-Function Relationships in Protein Families
10. Enzymes: Classification, Kinetics, and Control
11. The Cytochromes P450 and Nitric Oxide Synthases
12. Biological Membranes: Structure and Membrane Transport
13. Fundamentals of Signal Transduction
14. Bioenergetics and Oxidative Metabolism
15. Carbohydrate Metabolism I: Major Metabolic Pathways and Their Control
16. Carbohydrate Metabolism II: Special Pathways and Glycoconjugates
17. Lipid Metabolism I: Synthesis, Storage, and Utilization of Fatty Acids and Triacylglycerols
18. Lipid Metabolism II: Pathways of Metabolism of Special Lipids
19. Amino Acid Metabolism
20. Purine and Pyrimidine Nucleotide Metabolism
21. Iron and Heme Metabolism
22. Metabolic Interrelationships
23. Biochemistry of Hormones
24. Molecular Cell Biology
25. Cell Cycle, Programmed Cell Death and Cancer
26. Digestion and Absorption of Basic Nutritional Constituents
27. Principles of Nutrition I: Macronutrients
28. Principles of Nutrition II: Micronutrients

Glossary
Index

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