Practical Aging Reference from C.H.I.P.S.
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Understanding the Process of Aging
The Roles of Mitochondria, Free Radicals, and
Antioxidants
edited by Enrique Cadenas and Lester Packer
This innovative reference explores a wide selection of topics associated with
aging, providing a solid understanding of the significance and molecular
basis of the aging process and charting the course of future research in the area.
Stresses the interplay of mitochondria, mitochondrial DNA, oxidants, and antioxidants!
Featuring the research of over 55 experts in the area, Understanding the Process of
Aging
- covers the functions of nitric oxide and peroxynitrite in mitochondria
- integrates several views on the role of mitochondria in the development of apoptosis
- gives a quantitative analysis of mutations of mitochondrial DNA during human aging
- highlights mitochondrial free radical production
- introduces new roles of ubiquinone in mitochondrial functions
- offers new antioxidant-based complementary therapeutic strategies
- details aspects of intact cells and whole organisms in health and disease
- and more!
Featuring over 1800 references, tables, drawings, and photographs,
Understanding the Process of Aging benefits nutritionists and dieticians,
geriatricians, cell and molecular biologists, chemists and biochemists,
pharmacologists, biotechnologists, neurologists, cardiologists, oncologists,
dermatologists, and students in these disciplines.
Contents
- The Mitochondrial Production of Oxygen Radicals and Cellular Aging
- Walking a Tightrope: The Balance Between Mitochondrial Generation and Scavenging of Superoxide Anion
- The Biochemistry of Nitric Oxide and Peroxynitrite: Implications for Mitochondrial Function
- Oxygen-Dependent Regulation of Biological Functions by Nitric Oxide
- Production of Reactive Oxygen Species in Mitochondria and Age-Associated Pathophysiology: A Reality Check
- Functional Roles of Ubiquinone
- Mitochondrial Generation of Reactive Oxygen Species and Oxidative Damage During Aging: Roles of Coenzyme Q and Tocopherol
- Mitochondria and Aging: The Mouse's Tale
- Mitochondria and Apoptosis
- Role of Mitochondria in Oxidative Stress Associated with Aging and Apoptosis: Studies in Intact Cells
- The Mitochondrial-Lysosomal Axis Theory of Cellular Aging
- Quantitative Analysis of Mutations of Mitochondrial DNA During Human Aging
- Oxidative Damage and Fragility of Mitochondrial DNA
- Mitochondria in Cellular Aging and Degeneration
- Mitochondrial Alteration in Aging and Inflammation: A Possible Site of Action of Nitrone-Based Free Radical Traps
- Muscle Mitochondrial Transmembrane Processes in Mitochondriocytopathies
Index
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Understanding the Process of Aging
The Roles of Mitochondria, Free Radicals, and
Antioxidants
edited by Enrique Cadenas and Lester Packer
1999 • 392 pages • $198.95 + shipping
Texas residents please add 6.75 % sales tax
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