Metabolic Engineering offers a systematic analysis of complex metabolic pathways and ways of employing recombinant DNA techniques to alter cell behavior, metabolic patterns, and product formation.

Features:

• Showcases methods of toxic waste management
• Investigates engineering strategies for increased production of bulk or specialty chemicals
• Covers design and production of novel metabolites by polyketide synthesis,
• Illustrates navigation of metabolic pathways in mammalian cell systems and new approaches to the degradation of xenobiotics

Contents

• Introduction to metabolic engineering
• Metabolic flux balance analysis
• Engineering of the central metabolism of escherichia coli
• Metabolic engineering of escherichia coli for the production of aromatic compounds
• New tools for metabolic engineering os escherichia coli
• Metabolic engineering strategies for the production of polyhydroxyalkanoates, a family of biodegradable polymers
• Amino acid production - principles of metabolic engineering
• Metabolic engineering of antibiotic biosynthesis for process improvement
• The generation of organic molecule diversity through metabolic engineering
• On-line metabolic flux analysis for fermentation operation
• Metabolic engineering of clostridium acetobutylicum
• Metabolic engineering of yeast for substrate utilization and metabolite production
• Engineering heterologous secretion in yeast
• Metabolic engineering for the production of plant secondary metabolites
• Metabolic engineering of mammalian cells molecular bioremediation - metabolic engineering for biodegradation of recalcitrant pollutants

Index

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