Molecular Farming:
Plant-made Pharmaceuticals and Technical Proteins
edited by Rainer Fischer

Here, authors from academia and industry provide an exciting overview of current production technologies and the fascinating possibilities for future applications.

Topics include:

• Chloroplast-derived antibodies
• Biopharmaceuticals and edible vaccines
• Production of antibodies in plants and plant cell suspension cultures
• Production of spider silk proteins in plants
• Glycosylation of plant produced proteins

The whole is rounded off by chapters on the demands and expectations made on molecular farming by pharmaceutical corporations and the choice of crop species in improving recombinant protein levels.

Molecular Farming is of interest to biotechnologists, gene technologists, molecular biologists and protein biochemists in university as well as the biotechnological and pharmaceutical industries.

Contents

1. Efficient and Reliable Production of Pharmaceuticals in Alfalfa
2. Foreign Protein Expression Using Plant Cell Suspension and Hairy Root Cultures
3. Novel Sprouting Technology for Recombinant Protein Production
4. Monocot Expression Systems for Molecular Farming
5. The Field Evaluation of Transgenic Crops Engineered to Produce Recombinant Proteins
6. Plant Viral Expression Vectors: History and New Developments
7. Production of Pharmaceutical Proteins in Plants and Plant Cell Suspension Cultures
8. Chloroplast Derived Antibodies, Biopharmaceuticals and Edible Vaccines
9. Plant-derived Vaccines: Progress and Constraints
10. Production of Secretory IgA in Transgenic Plants
11. Production of Spider Silk Proteins in Transgenic Tobacco and Potato
12. Gene Farming in Pea Under Field Conditions
13. Host Plants, Systems and Expression Strategies for Molecular Farming
14. Downstream Processing of Plant-derived Recombinant Therapeutic Proteins
15. Glycosylation of Plant-made Pharmaceuticals
16. Biosafety Aspects of Molecular Farming in Plants
17. A Top-down View of Molecular Farming from the Pharmaceutical Industry: Requirements and Expectations
18. The Role of Science and Discourse in the Application of the Precautionary Approach

Subject Index

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