Pediatric Solid Organ Transplantation is a comprehensive and succinct text on all aspects of pediatric solid organ transplantation.

Pediatric Solid Organ Transplantation provides a ready source of reference, on both the basic science and organ specific surgical technique and after care.

Pediatric Solid Organ Transplantation offers:

• Definitive reference for all those interested in improving the care and quality of children undergoing solid organ transplantation
• Section on immunosuppressin expanded by four chapters
• Coverage of topics related to quality of life that affect survivors of pediatric transplanation
• International editorial and contributor team with both recognized leaders and emerging experts

Contents

Immunology and Genetics

1. The Immune Response to Organ Allografts
2. Allorecognition Pathways
3. Costimulation
4. The HLA System and Histocompatibility Testing for Organ Transplantation
5. Gene Polymorphisms and Pharmacogenomics
6. Genomics and Proteomics as Research Tools
7. Tolerance: A Review of its Mechanisms in the Transplant Setting

Immunosuppression and its Complications

8. Mechanisms of Action of Immunosuppressive Agents
9. Induction and Maintenance Immunosuppression
10. Novel Immunosuppressants
11. Therapies for the Allosensitized Patient
12. Infections Post-Transplantation
13. Post-Transplant Lymphoproliferative Disorders and Malignancy
14. Organ Toxicities

Kidney Transplantation

15. Historical Notes
16. Recipient Characteristics
17. Evaluation of the Candidate
18. Donor Evaluation, Surgical Technique and Perioperative Management
19. Pathology of the Kidney Allograft
20. Post-Transplant Management
21. Outcomes and Risk Factors

Liver Transplantation

22. Historical Notes
23. Recipient Characteristics
24. Evaluation of the Candidate
25. Donor Evaluation, Surgical Technique and Perioperative Management
26. Pathology of the Liver Allograft
27. Post-Transplant Management
28. Outcomes and Risk Factors

Heart Transplantation

29. Historical Notes
30. Recipient Characteristics
31. Evaluation of the Candidate
32. Donor Evaluation, Surgical Technique and Perioperative Management
33. Pathology of the Cardiac Allograft
34. Post-Transplant Management
35. Outcomes and Risk Factors

Lung and Heart-Lung Transplantation

36. Historical Notes
37. Recipient Characteristics
38. Evaluation of the Candidate
39. Donor Evaluation, Surgical Technique and Perioperative Management
40. Pathology of the Lung Allograft
41. Post-Transplant Management
42. Outcomes and Risk Factors

Intestinal Transplantation

43. Historical Notes
44. Recipient Characteristics
45. Evaluation of the Candidate
46. Donor Evaluation, Surgical Technique and Perioperative Management
47. Pathology of the Intestinal Allograft
48. Post-Transplant Management
49. Outcomes and Risk Factors

Special Issues after Pediatric Transplantation

50. Growth and Puberty
51. Cognitive Development
52. Psychosocial Adaptation and Adherence
53. Pregnancy
54. Gynecologic Issues
55. Transition to Adult Care

Index

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