Pharmacogenetics spans the wide array of technical, methodological, regulatory, and ethical issues related to pharmacogenetics and stresses the impact of pharmacogenetic data on patient care and management.

Features:

• Explains how genetic variation contributes to differing patient responses to medicines, including chemotherapy
• Emphasizes how pharmacogenetics will alter the diagnosis, classification, and treatment of common diseases
• Demonstrates the role of pharmacogenetics in the development of patient-tailored medications
• Discusses variability in drug metabolism enzyme pathways

Contents

Principles of Pharmacogenetics

• Identification of Treatment Response Genes
• Methods of Genotyping
• Pharmacoproteomics
• Potential Social, Ethical Issues Raised by the Development of Pharamacogenetics

Clinical Practice and Pharmacogenetics

• Pharmacogenetics of Adverse Drug Reactions
• Pharamcogenetics of Respiratory Disease
• Hematological Pharmacogenetics
• Pharmacogenetics in Oncology
• Pharmacogenetics in Infectious Diseases
• Pharmacogenetics in Rheumatology
• Polymorphisms in Cardiovascular Medicine
• Pharmacogenetics and Metabolic Disease
• Pharmacogenetics in Gastroenterology
• The Genetics of Antipsychotic Response

Index

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