Principles and Practice of Radiation Oncology, 5th edition has been completely overhauled to better represent the rapidly changing field of radiation oncology. This edition has an updated interior design including full-color throughout, and a new companion Website featuring the fully searchable text with all the images.
This comprehensive textbook provides an understanding of every aspect of radiation oncology:
- the natural history of cancer
- the physical methods of radiation application
- the effects of irradiation on normal tissues
- site-specific applications of radiation therapy either as a single modality or as part of a multimodality treatment program
This edition places greater emphasis on use of radiation oncology in palliative and supportive care as well as therapy.
Six new chapters cover:
- stereotactic irradiation outside the CNS
- photodynamic therapy
- radiation and gene therapy
- prostate—intermediate and high risk
- oncologic imaging/oncologic anatomy
- economics of radiation oncology
Other highlights include expanded coverage of new molecular biology and targeted therapies and greater emphasis on dose conformality, IMRT, IGRT, new radiation therapy delivery machines, radiosurgery, dose painting, and innovative brachytherapy.
Contents:
Section I: Overview and Basic Science of Radiation Oncology
- The Discipline of Radiation Oncology
- Biologic Basis of Radiation Therapy
- Molecular Cancer and Radiation Biology
- Molecular Pathophysiology of Tumors
- Principles of Radiologic Physics, Dosimetry, and Treatment Planning
- Photon External-Beam Dosimetry and Treatment Planning
- Electron-Beam Therapy: Dosimetry, Planning, and Techniques
- Three-Dimensional Conformal Radiation Therapy: Physics, Treatment Planning, and Clinical Aspects
- Intensity-Modulated Radiation Treatment Techniques and Clinical Applications
- Image-Guided Radiation Therapy
Section II: Techniques, Modalities, and Modifiers in Radiation Oncology
- Chapter 11 Altered Fractionation Schedules
- Late Effects of Cancer Treatment on Normal Tissues
- Methodology of Clinical Trials
- Total-Body and Hemibody Irradiation
- Stereotactic Radiosurgery and Radiotherapy
- Stereotactic Irradiation of Tumors Outside the Central Nervous System
- Intraoperaataive Radiotherapy
- Particle Beam Radiotherapy
- Physics and Biology of Brachytherapy
- Clinical Applications of Brachytherapy: Low-Dose-Rate and Pulse-Dose-Rate
- The Physics and Dosimetry of high-Dose-Rate Brachytherapy
- Clinical Aspects and Applications of High-Dose-Rate Brachytherapy
- Radioimmunoglobulins and Nonsealed Radionuclide Therapy
- Photodynamic Therapy
- Radiation Oncology in the Developing World
- Chemical Modifiers of Radiation Response
- Oncologic Imaging/Oncologic Anatomy
- Hyperthermia
- Basic Concepts of Chemotherapy and Irradiation Interaction
Section III: Clinical Radiation Oncology
- Skin
- Malignant Neoplasms Associated with the Acquired Immunodeficiency Syndrome
- Primary Intracranial Neoplasms
- Pituitary
- Spinal Canal
- Eye and Orbit
- Ear
- The Role of Combined Radiotherapy and Chemotherapy in the Management of Locally Advanced Squamous Carcinoma of the Head and Neck
- Nasopharynx
- Nasal Cavity and Paranasal Sinuses
- Salivary Glands
- Oral Cavity Cancer
- Oropharynx
- Hypopharynx Cancer
- Larynx
- Unusual Nonepithelial Tumors of the Head and Neck
- Management of the Neck Including Unknown Primary Tumor
- Thyroid
- Lung
- Mediastinum and Trachea
- Esophageal Cancer
- Tumors of the Heart and Great Vessels
- Breast: Stage Tis
- Early Stage Breast Cancer
- Breast Cancer
- Stomach
- Cancer of the Pancreas
- Liver and Hepatobiliary Tract
- Colon and Rectum
- Anal Cancer
- Kidney, Renal Pelvis, and Ureter
- Bladder PART I: MALE GENITOURINARY TUMORS
- Low-Risk Prostate Cancer
- Intermediate-and High-Risk Prostate Cancer
- Testis
- Penis and Male Urethra
- Uterine Cervix
- Endometrium
- Ovary
- Fallopian Tube
- Vagina
- Female Urethra
- Carcinoma of the Vulva
- Retroperitoneum
- Adrenal Gland
- Hodgkin Lymphoma
- Non-Hodgkin's Lymphoma
- Cutaneous T-Cell Lymphoma
- Leukemia
- Plasma Cell Myeloma and Plasmacytoma
- Osteosarcoma
- Soft Tissue Sarcomas (Excluding Retroperitoneum)
- Central Nervous System Tumors in Children
- Wilms' Tumor
- Neuroblastoma
- Rhabdomyosarcoma
- Ewing Tumor
- Lymphomas in Children
- Unusual Tumors in Childhood PART O: BENIGN DISEASES
- Radiotherapy of Non-Malignant Diseases
- Endovascular Brachytherapy
Section IV: Palliative and Supportive Care
- Palliation of Brain and Spinal Cord Metastases
- Palliation of Bone Metastases
- Palliation of Visceral recurrences and Metastases
- Pain Management
- Supportive Care and Quality of Life Section V Economics, Ethics, and Technology Assessment
Section V: Economics, Ethics, and Technology Assessment
- Technology Assessment, Cost Benefit, Outcome Analysis Research and Evidence-Based Radiation Oncology
- Ethics, Professional Values, and Legal Considerations in Radiation Oncology
- The Economics of Radiation Oncology
Index
to see books • videos • cd-roms of related interest